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A Case of Idiopathic Aquagenic Wrinkling of the Palms Successfully Treated with 20% Aluminum Chloride Hexahydrate.
Ann Dermatol
November 2023
Department of Dermatology, Korea University Ansan Hospital, Ansan, Korea.
Aquagenic keratoderma.
Bol Med Hosp Infant Mex
July 2022
Servicio de Anatomía Patológica Pediátrica, Unidad Médica de Alta Especialidad, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social. Ciudad de México, México.
Background: Aquagenic keratoderma is triggered in the palms and soles after contact with water, and is characterized by the appearance of translucent papules forming macerated plaques. It may be associated with medications and diseases such as cystic fibrosis, atopy, and malnutrition, or be idiopathic.
Case Report: We describe the case of a 17-year-old female patient with chronic functional abdominal pain.
Aquagenic (pseudo) keratoderma (aquagenic palmoplantar keratoderma, aquagenic wrinkling of palms).
Clin Dermatol
November 2021
Dermatology Clinic, Department of Medical Science and Public Health, University of Cagliari, Cagliari, Italy.
Aquagenic palmoplantar keratoderma (APK) is an uncommon hereditary or sporadic condition that is characterized by edematous flat-topped papules appearing on palmar skin with wrinkling after brief water exposure. APK has been associated with cystic fibrosis (CF), presenting with the same mutations found in CF (usually ΔF508 of the CFTR gene), either homozygous or heterozygous. APK may be idiopathic or drug-induced.
View Article and Find Full Text PDFTherapeutic Use of Botulinum Neurotoxins in Dermatology: Systematic Review.
Toxins (Basel)
February 2021
Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60020 Ancona, Italy.
Botulinum toxin is a superfamily of neurotoxins produced by the bacterium Clostridium Botulinum with well-established efficacy and safety profile in focal idiopathic hyperhidrosis. Recently, botulinum toxins have also been used in many other skin diseases, in off label regimen. The objective of this manuscript is to review and analyze the main therapeutic applications of botulinum toxins in skin diseases.
View Article and Find Full Text PDFAquagenic pruritus in an adolescent effectively managed with β-alanine supplementation.
Pediatr Dermatol
January 2021
Stanford University School of Medicine, Stanford, CA, USA.
Aquagenic pruritus is a rare debilitating condition, which can be idiopathic, iatrogenic, or associated with systemic disease. In idiopathic cases, treatment can be challenging as options are limited and of variable efficacy. Here, we report the case of a teenage boy with refractory idiopathic aquagenic pruritus effectively managed with administration of β-alanine supplementation, a treatment gaining traction in lay media but not yet reported in the medical literature.
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