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| http://dx.doi.org/10.1097/EJA.0000000000000411 | DOI Listing |
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Gas transport mechanisms during high-frequency ventilation.
Respir Res
December 2024
Department of Mechanical and Product Design Engineering, Swinburne University of Technology, Hawthorn, VIC, Australia.
By virtue of applying small tidal volumes, high-frequency ventilation is advocated as a method of minimizing ventilator-induced lung injury. Lung protective benefits are established in infants, but not in other patient cohorts. Efforts to improve and extend the lung protection potential should consider how fundamental modes of gas transport can be exploited to minimize harmful tidal volumes while maintaining or improving ventilation.
View Article and Find Full Text PDFThe role of pleural pressure in inducing pneumothorax and other adverse effects of positive pressure ventilation.
J Thorac Dis
November 2024
Department of Anesthesiology, Radboud University Medical Centre, Nijmegen, The Netherlands.
Mechanical ventilation, essential for critically ill patients, contrasts with natural respiration, primarily due to differences in pleural pressure ( ). Natural inspiration decreases , pulling the lungs away from the thoracic wall, whereas positive pressure inspiration increases , pushing the lungs against the thoracic wall. This shift has several consequences.
View Article and Find Full Text PDFActivation thresholds for electrical phrenic nerve stimulation at the neck: evaluation of stimulation pulse parameters in a simulation study.
J Neural Eng
November 2024
Institute of Biomedical Engineering and Informatics, TU Ilmenau, Ilmenau, Germany.
Phrenic nerve stimulation reduces ventilator-induced-diaphragmatic-dysfunction, which is a potential complication of mechanical ventilation. Electromagnetic simulations provide valuable information about the effects of the stimulation and are used to determine appropriate stimulation parameters and evaluate possible co-activation.Using a multiscale approach, we built a novel detailed anatomical model of the neck and the phrenic nerve.
View Article and Find Full Text PDFEffect of high-frequency oscillatory ventilation with intermittent sigh breaths on carbon dioxide levels in neonates.
Clin Exp Pediatr
November 2024
Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Background: High-frequency oscillatory ventilation (HFOV) minimizes ventilator-induced lung injuries. Spontaneous sigh breathing may augment the functional residual capacity, increase lung compliance, and recruit atelectatic alveoli.
Purpose: To evaluate the difference in the partial pressure of carbon dioxide (PaCO2) in neonates receiving invasive HFOV as the primary mode of respiratory support before versus after sigh breaths (Sighs).
Protective mechanical ventilation in critically ill patients after surgery.
Curr Opin Crit Care
December 2024
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Purpose Of Review: This review aims to provide an updated overview of lung protective strategies in critically ill patients after surgery, focusing on the utility of postoperative open-lung ventilation during the transition from the operating room to the intensive care unit.
Recent Findings: Mechanically ventilated patients after surgery represent a challenge in the intensive care unit. Different protective strategies have been proposed to minimize the risk of ventilator-induced lung injury (VILI) and facilitate adequate weaning from mechanical ventilation.
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