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Diagnosis and Management of Acute Appendicitis in Adults: A Review.
JAMA
December 2021
Department of Surgery, Duke University Medical Center, Durham, North Carolina.
Importance: Acute appendicitis is the most common abdominal surgical emergency in the world, with an annual incidence of 96.5 to 100 cases per 100 000 adults.
Observations: The clinical diagnosis of acute appendicitis is based on history and physical, laboratory evaluation, and imaging.
Prophylactic antibiotics for penetrating abdominal trauma.
Cochrane Database Syst Rev
December 2019
University of the Witwatersrand, General Surgery/Trauma Unit, PO Box 91155, Auckland Park, Johannesburg, Gauteng, South Africa, 2006.
Background: Penetrating abdominal trauma occurs when the peritoneal cavity is breached. Routine laparotomy for penetrating abdominal injuries began in the 1800s, with antibiotics first being used in World War II to combat septic complications associated with these injuries. This practice was marked with a reduction in sepsis-related mortality and morbidity.
View Article and Find Full Text PDFManagement of acute appendicitis in adults: A practice management guideline from the Eastern Association for the Surgery of Trauma.
J Trauma Acute Care Surg
July 2019
From the The Ohio State University (A.R.), Columbus, OH; Tufts Medical Center (N.B.), Boston, Massachusetts; The Johns Hopkins University (C.J., E.R.H.), Baltimore, Maryland; MetroHealth Medical Center (J.J.C.), Cleveland, Ohio; Cooper University (N.F.), Camden, New Jersey; University of Texas Southwestern (M.C.), Dallas, Texas; University of Washington-Harborview (B.R.), Seattle, Washington; University of Colorado (C.V.), Aurora, Colorado; and Weill Cornell Medicine (M.N.), New York, New York.
Background: Acute appendicitis (AA) has been considered one of the most common acute surgical conditions in the world. Recent studies, however, have suggested that nonoperative management (NOM) with a course of antibiotics (ABX) may be as effective as surgery in treating appendicitis. As there are evolving perspectives regarding the optimal therapy for appendicitis, we sought to provide recommendations regarding the role of NOM with the administration of antibiotics (antibiotics-first approach) in uncomplicated AA as well as the need for routine interval appendectomy (RIA) in those presenting with appendiceal abscess or phlegmon (AAP) initially managed without appendectomy.
View Article and Find Full Text PDFSuccessful surgical management of non-perforating acute appendicitis with septic disseminated intravascular coagulation: A case report and review of the literature.
Int J Surg Case Rep
January 2019
Department of Gastroenterological Surgery, Hiroshima City Asa Citizens Hospital, Japan.
Introduction: Perforating appendicitis and abscess-forming appendicitis may cause septic disseminated intravascular coagulation (DIC). However, non-perforating acute appendicitis with septic DIC is extremely rare.
Presentation Of Case: A 67-year-old man was referred to our hospital one day after starting oral antibiotic treatment for acute appendicitis.
Antibiotics-first strategy for uncomplicated acute appendicitis in adults is associated with increased rates of peritonitis at surgery. A systematic review with meta-analysis of randomized controlled trials comparing appendectomy and non-operative management with antibiotics.
Surgeon
October 2017
General Surgery, Montichiari Surgery, ASST Spedali Civili di Brescia, Brescia, Italy.
Background: Acute appendicitis is the most common surgical diagnosis in young patients, with lifetime prevalence of about 7%. Debate remains on whether uncomplicated AA should be operated or not. Aim of this meta-analysis of randomized controlled trials was to assess current evidence on antibiotic treatment for uncomplicated AA compared to standard surgical treatment.
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