Objective: To investigate the clinical, endoscopic and pathologic characteristics of gastric hyperplastic polyps.
Methods: A total of 1 676 gastric hyperplastic polyps patients diagnosed by gastroscopy and pathology from January 2005 to October 2014 were enrolled and analyzed retrospectively.
Results: Among them, 1 030 patients (61.46%) were female, 1 014 patients (60.50%) aged ≥ 60 years old, 1 093 patients (65.21%) polyps distributed in the fundus and body of stomach. And the concurrent conditions included dysplasia in polyps tissue (n = 89, 5.31%), intestinal metaplasia (n = 94, 5.61%), focal carcinoma (n = 5, 0.30%). In the background gastric mucosa included Helicobacter pylori gastritis (n = 368, 21.96%), autoimmune gastritis (n = 238, 14.20%), intestinal metaplasia (n = 379, 22.61%), dysplasia (n = 110, 6.56%), adenocarcinoma (n = 13, 0.78%), carcinoid tumor (n = 3, 0.18%).
Conclusions: Hyperplastic polyps are mainly distributed in the proximal stomach, and malignant transformation may be detected in hyperplastic polyps. Whereas, both precancerous lesions and malignant transformation are detected in background gastric mucosa. Therefore, the endoscopist should always pay attention to background gastric mucosa.
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