AI Article Synopsis
- A new compound called hexapetarin, alongside three other xanthones and four triterpenoids, was extracted from the stem bark of the Malaysian plant Mesua hexapetala.
- The chemical structures of these compounds were identified using techniques like NMR (Nuclear Magnetic Resonance) and MS (Mass Spectrometry).
- Hexapetarin showed moderate anti-inflammatory properties, while one specific xanthone demonstrated strong anti-inflammatory effects.
Article Abstract
A new alkylated coumarin derivative, hexapetarin (1) along with three other xanthones, trapezifolixanthone (2), cudraxanthone G (3) and 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4), and four common triterpenoids, friedelin (5), stigmasterol (6), beta-sitosterol (7) and gamma-sitosterol (8) were isolated from the stem bark of Mesua hexapetala (Clusiaceae), a plant, native to Malaysia. The structures of these compounds were elucidated and determined using spectroscopic techniques such as NMR and MS. Anti-inflammatory activity assay indicated hexapetarin (1) to possess moderate anti-inflammatory activity, while 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4) gave very good activity.
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| http://dx.doi.org/10.1080/14786419.2015.1120727 | DOI Listing |
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