Metronidazole-induced encephalopathy (MIE) is a rare cause of drug-induced toxic encephalopathy. We report the clinical and neuroimaging findings of a patient with chronic diarrhoea who developed metronidazole-induced encephalopathy. After the drug was discontinued there was complete reversal of the condition.
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An Unusual Case of Metronidazole-induced Encephalopathy in a Patient with Hereditary Hemorrhagic Telangiectasia.
J Community Hosp Intern Med Perspect
September 2024
Department of Medicine, Division of General Internal Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Metronidazole-induced encephalopathy (MIE) is a rare toxic encephalopathy. We describe a reversible MIE case in a patient with hereditary hemorrhagic telangiectasia (HHT), treated with metronidazole for brain abscess, who developed dizziness, weakness, dysarthria, and severe dysmetria. His Magnetic Resonance Imaging (MRI) brain revealed bilateral, symmetric lesions in bilateral symmetrical regions of increased intensity in the medullary olives, cerebellar dentate nuclei, and the dorsal pons, all characteristic of MIE.
View Article and Find Full Text PDF[A case of metronidazole-induced encephalopathy that is difficult to differentiate from Wernicke encephalopathy].
Rinsho Shinkeigaku
September 2024
Department of Internal Medicine, Kawasaki Medical School, General Medical Center.
Herein, we present the case of a 76-year-old man diagnosed with an iliopsoas abscess 3 months prior and consequently administered metronidazole. The patient visited our facility complaining of difficulty in speaking and feeling unsteady when walking. Neurological findings showed dysarthria, nystagmus, and bilateral cerebellar ataxia.
View Article and Find Full Text PDFMetronidazole-induced encephalopathy in a patient with spondylodiscitis.
Clin Toxicol (Phila)
September 2024
Serviço de Imagiologia Neurológica, Unidade Local de Saúde Santa Maria, Lisboa, Portugal.
Article Synopsis
- Metronidazole-induced encephalopathy is a rare and serious side effect of a medicine called metronidazole that can affect the brain.
- Doctors think it might have something to do with how it interacts with molecules in the body, but they are not completely sure why it happens.
- A 63-year-old man who took this medicine experienced brain problems, but when doctors recognized the issue and stopped the medicine, he started to feel better quickly.
Metronidazole-Induced Encephalopathy With Probable Crohn Encephalitis: A Case Report.
Clin Neuropharmacol
May 2024
Gastro-entero-hepatology, Mohammed VI University Medical Center, Marrakesh, Morocco.
Objectives: Metronidazole central nervous system toxicity is a rare finding in patients receiving the medication. We report a peculiar case of metronidazole central nervous system toxicity in which both the underlying condition (Crohn disease) and the drugs used to treat it are potential causes of encephalopathy.
Methods: A 26-year-old female with 6-year history of Crohn's disease for 6 years presented acute-onset encephalopathy.
Metronidazole-Induced Acute Cerebellitis in a Young Patient: Unusual Onset, Delayed Remission, and Characteristic Imaging Features.
Cureus
March 2024
Department of General Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Metronidazole-induced acute cerebellitis is an exceptionally rare condition resulting from severe adverse reactions to metronidazole, a medication generally employed in the management of infections caused by anaerobic microbes. Although neuropathy has been linked to metronidazole use, reports of acute cerebellitis are infrequent. The neurological effects associated with metronidazole can include weakness, dysarthria, postural instability, seizures, giddiness, vertigo, ataxia, confusion, encephalopathy, headaches, and tremors.
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