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Background: "Active" heat acclimation (exercise-in-the-heat) can improve exercise performance but the efficacy of "passive" heat acclimation using post-exercise heat exposure is unclear. Therefore, we synthesised a systematic review and meta-analysis to answer whether post-exercise heat exposure improves exercise performance.

Methods: Five databases were searched to identify studies including: (i) healthy adults; (ii) an exercise training intervention with post-exercise heat exposure via sauna or hot water immersion (treatment group); (iii) a non-heat exposure control group completing the same training; and (iv) outcomes measuring exercise performance in the heat (primary outcome), or performance in thermoneutral conditions, V̇Omax, lactate threshold, economy, heart rate, RPE, core temperature, sweat rate, and thermal sensations.

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Introduction: For patients with breast cancer receiving preoperative neoadjuvant chemotherapy with anthracyclines, there is an increased risk of postoperative myocardial injury due to the cardiotoxicity of the chemotherapeutic agents. The optimal intraoperative blood pressure regulation regimen for these patients is unclear. This study is being conducted to determine whether targeting mean arterial pressure (MAP) to 100%-120% of the patient's baseline blood pressure reduces the incidence of myocardial injury after non-cardiac surgery (MINS) compared with targeting MAP to 80%-100%.

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Background: Peak oxygen uptake (VO) is considered the most important indicator of aerobic exercise capacity during cardiopulmonary exercise testing (CPET). However, its accuracy is compromised when maximal effort is not achieved. In such cases, submaximal parameters can serve as surrogates for assessing exercise performance.

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Purpose: The purpose of this study was to examine the sex-specific influence of expected exercise duration on the physiological responses to RPE-clamp exercise anchored to RPE 15 with participants being deceived into believing the RPE-clamp exercise would last for 20-, 30-, or 40-min, but all trials were 30-min.

Methods: Twelve males and 12 females completed a graded exercise test followed by randomly ordered RPE-clamp trials at RPE15 on the Borg 6-20 scale where subjects were deceived into expecting exercise to last for either 20-, 30-, or 40-min, but the actual duration for each trial was 30-min. Separate 2 (Sex [Male vs.

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Hypermagnesemia- and Hyperphosphatemia-Associated Cardiac Arrest after Injection of a Novel Magnesium-Based Bone Cement in Spinal Surgery.

J Am Acad Orthop Surg Glob Res Rev

January 2025

From the Department of Orthopaedic Surgery, Singapore General Hospital, Singapore (Dr. Loh, Dr. Ling, Dr. Jiang, and Lim) and the Department of Surgical Intensive Care, Division of Anaesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore (Dr. Goh).

We report a case of pulseless electrical activity (PEA) associated with profound hypermagnesemia immediately after cementation of a novel magnesium-based cement in spine surgery. During T8 to T12 posterior instrumentation and decompression laminectomy for vertebral metastasis secondary to lung cancer, a 61-year-old Chinese woman developed sudden hypotension and went into PEA immediately after injection of a novel magnesium-based cement. Intraoperative fluoroscopic imaging did not show any notable cement extravasation.

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