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Background And Aims: The prevalence of obesity and metabolic syndrome (MetS) is rising among liver transplant (LT) candidates, many of whom have Metabolic-Associated Steatotic Liver Disease (MASLD). Following LT, untreated obesity often causes recurrent MASLD. We treated patients with obesity with LT and concurrent sleeve gastrectomy (LTSG), aiming to determine long-term impact on obesity, MetS and recurrent MASLD after transplantation.
View Article and Find Full Text PDFNavigating the intricacies of a term neonate with coexistent giant omphalocele, right diaphragmatic hernia and partial Cantrell's pentalogy.
BMJ Case Rep
March 2025
Department of Pediatric Surgery, All India Institute of Medical Sciences, Vijaypur, Jammu, Jammu, Jammu and Kashmir, India
A term neonate (TN) of 2 days, delivered by lower segment caesarean section in a private nursing home of a rural area, was referred to the outpatient department of paediatric surgery with a chief concern of large abdominal swelling and mild respiratory distress. The TN was diagnosed with giant omphalocele and a right diaphragmatic hernia.Intraoperatively, the omphalocele sac was found to contain liver, stomach, spleen and small intestine, with the latter herniating through a right diaphragmatic defect.
View Article and Find Full Text PDFCase Report: Total intragastric mesh migration six years after diaphragmatic rupture and hiatal hernia surgery.
F1000Res
March 2025
General Surgery, Faculty of Medicine of Sousse, Sousse, Tunisia.
Background: Mesh implementation to repair the hiatal space is already justified. Nevertheless, the use of this procedure is debated in regard of complications that may occur. Mesh erosion and migration are considered the most serious complications of mesh repairs.
View Article and Find Full Text PDFArtificial intelligence-driven integration of single-cell RNA sequencing and transcriptome analysis to decipher APOE's role in gastric cancer prognosis and therapy.
Discov Oncol
March 2025
Department of Gastrointestinal and Hernia Surgery, People's Hospital of Guilin, Guilin, 541002, Guangxi, China.
Background: Gastric cancer (GC) remains a global health challenge due to its high mortality rate and the lack of specific diagnostic methods. Tumor heterogeneity significantly hinders effective treatment, necessitating advanced techniques to dissect its complexity. Artificial intelligence (AI) offers transformative potential in uncovering intricate cellular dynamics and gene regulatory networks.
View Article and Find Full Text PDFNomograms of risk prediction and prognosis for the T1-T2 stage gastric cancer with lymph node metastasis: a population-based study.
Front Med (Lausanne)
February 2025
Department of Colorectal Hernia Surgery, Binzhou Medical University Hospital, Binzhou, China.
Background And Aims: Lymph node metastasis plays a crucial role in determining the appropriate treatment approach for patients with gastric cancer (GC), particularly those in the T1-T2 stage. Currently available diagnostic strategies for GC with lymph nodes have limited accuracy. The present research aimed to create and validate diagnostic and prognostic nomograms specifically tailored for the T1-T2 stage GC patients with LNM.
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