Cross-reactivity between Lyme and syphilis screening assays: Lyme disease does not cause false-positive syphilis screens.

Diagn Microbiol Infect Dis

Department of Medicine, Nova Scotia Health Authority and Dalhousie University, Halifax, NS, Canada; Department of Pathology and Laboratory Medicine, Nova Scotia Health Authority, Halifax, NS, Canada; Department of Pathology, Dalhousie University, Halifax, NS, Canada.

Published: March 2016

Increased rates of Lyme disease and syphilis in the same geographic area prompted an assessment of screening test cross-reactivity. This study supports the previously described cross-reactivity of Lyme screening among syphilis-positive sera and reports evidence against the possibility of false-positive syphilis screening tests resulting from previous Borrelia burgdorferi infection.

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http://dx.doi.org/10.1016/j.diagmicrobio.2015.11.019DOI Listing

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