Increased rates of Lyme disease and syphilis in the same geographic area prompted an assessment of screening test cross-reactivity. This study supports the previously described cross-reactivity of Lyme screening among syphilis-positive sera and reports evidence against the possibility of false-positive syphilis screening tests resulting from previous Borrelia burgdorferi infection.
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http://dx.doi.org/10.1016/j.diagmicrobio.2015.11.019 | DOI Listing |
Microorganisms
October 2024
Center for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, RJ, Brazil.
Lyme disease, a zoonotic infection caused by the bacterium , is transmitted to humans through the bites of infected ticks. Its diagnosis primarily relies on serological methods; however, the existing borreliosis techniques have shown a variable sensitivity and specificity. Our study aimed to map IgG epitopes from five outer membrane proteins (Omp) from [Filament flagellar 41kD (PI1089), flagellar hook-associated protein (Q44767), Flagellar hook k2 protein (O51173), Putative Omp BURGA03 (Q44849), and 31 kDa OspA (P0CL66)] lipoprotein to find specific epitopes for the development of accurate diagnosis methods.
View Article and Find Full Text PDFMicrobiol Spectr
October 2024
EpitogenX Ltd, Foresterhill Health Campus, Aberdeen, United Kingdom.
Eur J Clin Microbiol Infect Dis
December 2024
Department of Medical Microbiology and Immunology, Diakonessenhuis Hospital, Utrecht, The Netherlands.
Int J Infect Dis
October 2024
Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, USA. Electronic address:
Objectives: Human babesiosis is an emerging and potentially fatal tick-borne disease caused by intraerythrocytic parasites of the Babesia genus. Among these, Babesia duncani is particularly notable for causing severe and life-threatening illness in humans. Accurate diagnosis and effective disease management hinge on the detection of active B.
View Article and Find Full Text PDFUnlabelled: Human babesiosis is a rapidly emerging and potentially fatal tick-borne disease caused by intraerythrocytic apicomplexan parasites of the genus. Among the various species of that infect humans, has been found to cause severe and life-threatening infections. Detection of active infection is critical for accurate diagnosis and effective management of the disease.
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