Numerical methods for simulating blood flow at macro, micro, and multi scales.

J Biomech

School of Engineering, Tohoku University, Sendai, Japan; Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan.

Published: July 2016

AI Article Synopsis

  • In the last ten years, numerical methods in computational biomechanics have improved to tackle challenges in simulating blood flow at various scales, from cells to organs.
  • These methods can be categorized based on the type of computational mesh they use, including fixed mesh, moving mesh, and mesh-free methods, each suited for different characteristics.
  • The overview highlights the recent advancements in simulating blood flow at both macro and micro scales, emphasizing the importance of computational meshes and multi-scale modeling techniques.

Article Abstract

In the past decade, numerical methods for the computational biomechanics of blood flow have progressed to overcome difficulties in diverse applications from cellular to organ scales. Such numerical methods may be classified by the type of computational mesh used for the fluid domain, into fixed mesh methods, moving mesh (boundary-fitted mesh) methods, and mesh-free methods. The type of computational mesh used is closely related to the characteristics of each method. We herein provide an overview of numerical methods recently used to simulate blood flow at macro and micro scales, with a focus on computational meshes. We also discuss recent progress in the multi-scale modeling of blood flow.

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Source
http://dx.doi.org/10.1016/j.jbiomech.2015.11.047DOI Listing

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