Background: Chronic obstructive pulmonary disease (COPD) affects >15 million individuals in the United States and is a common comorbidity in patients undergoing surgery; therefore, the association between COPD in patients and postoperative surgical outcomes was investigated. The objective of this study was to assess the associations between COPD and postoperative morbidity, mortality, and hospital duration of stay.
Methods: Patients who underwent cholecystectomy, appendectomy, small bowel resection, partial colectomy, hepatic resection, gastrectomy, pancreatectomy, and ventral hernia repair with and without COPD (n = 331,425) in the National Surgical Quality Improvement Program database from 2007 to 2010 were studied. The primary outcomes were 30-day morbidity, mortality, and hospital duration of stay; secondary outcomes were specific postoperative complications.
Results: COPD was present in 12,491 patients (3.8%) undergoing the abdominal operations surveyed. The 30-day morbidity and mortality rates and hospital duration of stay for patients undergoing all abdominal procedures reviewed was greater for patients with COPD compared with patients without COPD (all P < .0001, except hepatic resection). Multivariate analysis controlling for comorbidities revealed that COPD was associated independently with increased postoperative morbidity in all abdominal procedures reviewed, increased postoperative mortality after cholecystectomy, appendectomy, small bowel resection, and ventral hernia repair, and increased duration of stay after cholecystectomy, small bowel resection, partial colectomy, gastrectomy, pancreatectomy, and ventral hernia repair (all P < .05).
Conclusion: Patients with COPD undergoing operative procedures in the abdomen have increased morbidity, mortality, and duration of stay. This study highlights the importance of studying potential preoperative optimization of pulmonary status in patients with COPD before operation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.surg.2015.11.007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Deciphering the therapeutic effects of Xiyanping injection: insights into pulmonary and gut microbiome modulation, SerpinB2/PAI-2 targeting, and alleviation of influenza a virus-induced lung injury.
Virol J
January 2025
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 100010, China.
Infection with Influenza A virus (IAV) induces severe inflammatory responses and lung injury, contributing significantly to mortality and morbidity rates. Alterations in the microbial composition of the lungs and intestinal tract resulting from infection could influence disease progression and treatment outcomes. Xiyanping (XYP) injection has demonstrated efficacy in clinical treatment across various viral infections.
View Article and Find Full Text PDFAssessment of healthcare workers' knowledge and availability of resources for sickle cell disease management in Bukavu, Democratic Republic of the Congo.
BMC Health Serv Res
January 2025
Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo.
Introduction: Sickle cell disease (SCD) is a global public health priority due to its high morbidity and mortality. In the Democratic Republic of the Congo (DRC), effective care for this disease depends on the availability of resources and the level of knowledge of healthcare workers (HCWs). However, in Bukavu, there is limited data available on these two crucial aspects, which are vital for enhancing the care of patients with SCD.
View Article and Find Full Text PDFPrevalence of non-vaccine high-risk HPV cervical infections in vaccinated women: a systematic review and meta-analysis.
BMC Infect Dis
January 2025
Programa de Pós-graduação em Ciências Farmacêuticas, Escola de Farmácia, Universidade Federal de Ouro Preto, Ouro Preto, Minas Gerais, Brazil.
Background: Human Papillomavirus (HPV) is the most common sexually transmitted lower genital tract infection worldwide and the main etiological factor of cervical cancer (CC). Since 2006, vaccines have been implemented to reduce CC-related morbidity and mortality. This systematic review and meta-analysis aimed to evaluate the prevalence of cervical infections by non-vaccine high-risk HPV (HR-HPV) types in women vaccinated against types 16 and 18.
View Article and Find Full Text PDFComparing Operative Outcomes and Resection Quality in Robotic vs Open Pancreaticoduodenectomy: A Meta-analysis of 54,000 Patients.
J Gastrointest Cancer
January 2025
Dow University of Health Sciences, Karachi, Pakistan.
Background: High morbidity and mortality make pancreaticoduodenectomy (PD) one of the most complicated surgical procedures. This meta-analysis aimed to compare the outcomes of robotic pancreaticoduodenectomy (RPD) versus open pancreaticoduodenectomy (OPD).
Method: A comprehensive literature search of PubMed, Cochrane Central, and Google Scholar was conducted from inception to November 2024.
An integrated approach to predict genetic risk for Mosquito-Borne diseases in the local Population of Tehsil Haripur, Khyber Pakhtunkhwa, Pakistan.
Sci Rep
January 2025
Institute of Molecular Biology and Biotechnology (IMBB), The University of Lahore (UOL), Lahore, Pakistan.
Highly variable response shown by individuals against mosquito-borne infections suggests that host genetic factors play an important role in determining mosquito-borne disease onset. Therefore, it is necessary to determine the genetic risk of these diseases in specific populations. The current study aimed to determine the percentage of individuals in the general population carrying mosquito-borne disease susceptibility and protection-related variants.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!