Objectives: The aim of this review is to evaluate the ocular safety of orthokeratology (OrthoK) treatment of myopia correction and retardation.
Data Sources: Clinical studies published in English and Chinese were identified from MEDLINE, EMBASE CNKI, CQVIP, and WANFANG DATA (all from 1980 to April 2015). The reference lists of the studies and the Science Citation Index were also searched.
Selection Criteria: Relevant clinical studies including case series, case reports, patient/practitioner surveys, retrospective and prospective cohort studies, and clinical trials were all included in the review. The material of OrthoK lenses was limited to gas-permeable lens.
Main Results: This review incorporated a total of 170 publications, including 58 English and 112 Chinese literature. The risk of microbial keratitis in overnight OrthoK was similar to that of other overnight modality. The most common complication was corneal staining. Other clinically insignificant side effects included epithelial iron deposit, prominent fribrillary lines, and transient changes of corneal biomechanical properties. There was no long-term effect of OrthoK on corneal endothelium.
Conclusions: There is sufficient evidence to suggest that OrthoK is a safe option for myopia correction and retardation. Long-term success of OrthoK treatment requires a combination of proper lens fitting, rigorous compliance to lens care regimen, good adherence to routine follow-ups, and timely treatment of complications.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697954 | PMC |
| http://dx.doi.org/10.1097/ICL.0000000000000219 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Corneal astigmatism after temporary discontinuation from long-term spherical and toric orthokeratology.
Cont Lens Anterior Eye
January 2025
Laboratory of Optometry and Vision Sciences, West China School of Medicine, Sichuan University, Chengdu, China; Department of Optometry and Vision Sciences, West China School of Medicine, Sichuan University, Chengdu, China.
Objective: To investigate changes in corneal astigmatism (curvatures and corneal sagittal height difference (C-sagDiff) at 8-mm chord) after temporary discontinuation from long-term spherical and toric orthokeratology (ortho-k) lens wear in a Chinese population.
Methods: Relevant data were retrieved from 110 patients (55 wearing spherical ortho-k lenses, 55 wearing toric ortho-k lenses) who have been undergoing ortho-k treatment for at least one year and stopped lens wear temporarily for scheduled lens replacement. The topographic and refraction data at baseline and post-discontinuation was collected for all the patients.
Longitudinal changes in choroidal structures among children with low to moderate myopia under orthokeratology treatment.
Cont Lens Anterior Eye
December 2024
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China. Electronic address:
Purpose: To explore the longitudinal changes in choroidal features in myopic children with low to moderate myopia under orthokeratology (ortho-k) treatment.
Methods: Children (n = 80) aged 8-12 years with spherical equivalent refraction of -1.00 to -6.
Analysis of anterior corneal surface shape after replacing orthokeratology lenses carrying a small base curve diameter.
Front Neurosci
November 2024
Optometry Clinic Center, Wenzhou Medical University Eye Hospital, Wenzhou, Zhejiang, China.
Purpose: The study analyzed the changes in corneal surface shape after replacing orthokeratology lenses carrying a small base curve (BC) diameter.
Methods: In this retrospective study, we included ~54 right eyes belonging to 54 myopic children who insisted on wearing an orthokeratology (ortho-k BC 6.0 mm) lens for more than 12 months and then replaced the second ortho-k (BC 6.
Corneal elevation asymmetry vector: Viable predictor of severe one-year-averaged orthokeratology lens decentration.
Cont Lens Anterior Eye
February 2025
Department of Ophthalmology & Clinical Center of Optometry, Peking University People's Hospital, Beijing 100044, China; College of Optometry, Peking University Health Science Center, Beijing, China; Eye Disease and Optometry Institute, Peking University People's Hospital; Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases. Electronic address:
Background: To assess the predictive value of pretreatment corneal elevation asymmetry vector (CEAV) for severe orthokeratology (Ortho-k) lens decentration (LD) in Chinese myopic adolescents.
Methods: A retrospective analysis of 247 myopic participants over one year employed a novel MATLAB algorithm to calculate CEAV and precise LD vector. Subjects were categorized into mild (<1 mm) and severe (≥1 mm) yearly averaged LD (YALD) groups.
Epithelial and stromal thickness profile and lens decentration in myopic orthokeratology.
J Optom
October 2023
Ocular Surface and Contact Lens Research Laboratory, Faculty of Optics and Optometry, Universidade de Santiago de Compostela, Spain; Clínica Oftalmológica Dr. Parafita, Ribeira, Spain.
Purpose: To study topographic epithelial and total corneal thickness changes in myopic subjects undergoing successful orthokeratology treatment in connection with the objective assessment of contact lens decentration.
Methods: A prospective-observational and non-randomized study in 32 Caucasian myopic eyes undergoing Ortho-k for 3 months. Total, epithelial, and stromal thicknesses were studied before and after Ortho-k treatment, using optical coherence tomography with anterior segment application software.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!