AI Article Synopsis
- Neuropsychiatric systemic lupus erythematosus (SLE) includes various neurologic and psychiatric issues due to central nervous system involvement, with catatonia being a rare manifestation.
- Treatment options for neuropsychiatric SLE are not well-established, though benzodiazepines, immunosuppression, plasma exchange, and electroconvulsive therapy (ECT) have been explored.
- In a reported case of catatonia due to neuropsychiatric lupus, the patient did not improve with benzodiazepines or immunosuppression, but showed significant improvement with ECT, highlighting its potential effectiveness for resistant cases.
Article Abstract
Neuropsychiatric systemic lupus erythematous (SLE) encompasses various psychiatric and neurological manifestations that develop in SLE patients, secondary to involvement of central nervous system. Neuropsychiatric SLE, presenting as catatonia is very uncommon, and treatment of this condition is not well defined. Previously the role of benzodiazepines, immunosuppression, plasma exchange, and electroconvulsive therapy (ECT) has been described in its management. Here we describe a case of neuropsychiatric lupus presenting as catatonia that did not respond to benzodiazepines or immunosuppression. The symptoms of catatonia showed improvement with ECT. Furthermore, we have discussed the pathology of the disorder and the role of ECT in the treatment of cases of catatonia associated with SLE, who do not respond to benzodiazepines.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676217 | PMC |
| http://dx.doi.org/10.4103/0253-7176.168597 | DOI Listing |
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