Modulation instability is thoroughly investigated and a simple analytical model for its power critically modifying the wave properties in terms of system parameters is derived and experimentally validated. The differences on the modulation instability gain spectrum in lossless and lossy optical fibers are analyzed based on theoretical models and numerical simulations. In particular the impact of background noise on the behavior of modulation instability is studied analytically and verified by measurements and simulations. The proposed analytical model is experimentally validated by monitoring the wave propagation along an optical fiber using a Brillouin optical time-domain analyzer. This way, the evolution of the optical signal traveling through optical fibers, especially, the pump depletion and the recurrence phenomenon are investigated.
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http://dx.doi.org/10.1364/OE.23.029514 | DOI Listing |
Chirp modulation can generate a relatively flat electro-optic frequency comb (EO comb) and offers the advantage of frequency reconfigurability, demonstrating significant potential in high-precision sensing and absorption spectroscopy measurements. However, nonresonant devices such as waveguides are susceptible to limitations in modulation efficiency and bandwidth during electro-optic modulation. In this paper, by utilizing chirp modulation resonance mode, we have realized an EO comb based on a lithium niobate resonator with small tooth spacing and high flatness.
View Article and Find Full Text PDFJ Exp Clin Cancer Res
January 2025
Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanità, Rome, Italy.
Background: Bacterial toxins are emerging as promising hallmarks of colorectal cancer (CRC) pathogenesis. In particular, Cytotoxic Necrotizing Factor 1 (CNF1) from E. coli deserves special consideration due to the significantly higher prevalence of this toxin gene in CRC patients with respect to healthy subjects, and to the numerous tumor-promoting effects that have been ascribed to the toxin in vitro.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
City University of Hong Kong, Department of Physics and Materials Science, 83 Tat Chee Ave, Kowloon Tong, 999077, Hong Kong, HONG KONG.
Lithium metal batteries (LMBs) are regarded as the potential alternative of lithium-ion batteries due to their ultrahigh theoretical specific capacity (3860 mAh g-1). However, severe instability and safety problems caused by the dendrite growth and inevitable side reactions have hindered the commercialization of LMBs. To solve them, in this contribution, a design strategy of soluble lithiophilic covalent organic frameworks (COFs) is proposed.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Key Laboratory of Advanced Catalytic Materials and Reaction Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei 230009, China.
Photoelectrochemical (PEC) water splitting offers an ideal strategy for the development of clean and renewable energy. However, its practical implementation is often inhibited by the high recombination rate of photogenerated charge carriers and the instability of photoanodes. Introducing defect engineering (such as oxygen vacancies) and constructing internal electric field-modulated Z-scheme heteronanostructures (HNs) can be considered as effective approaches to overcome these obstacles.
View Article and Find Full Text PDFCrit Rev Oncol Hematol
January 2025
The Cancer Research Institute and the Second Affiliated Hospital, Hengyang Medical School, University of South China (USC), Hunan 421001, China; Hunan Provincial Key Laboratory of Basic and Clinical Pharmacological Research of Gastrointestinal Cancer, USC, Hunan 421001, China; MOE Key Lab of Rare Pediatric Diseases, Hengyang Medical School, USC, Hunan 421001, China; National Health Commission Key Laboratory of Birth Defect Research and Prevention, Hunan Provincial Maternal and Child Health Care Hospital, USC, Hunan 410008, China. Electronic address:
Colorectal cancer (CRC) is one of the most prevalent and lethal cancers worldwide, ranking third in incidence and second in mortality. While immunotherapy has shown promise in patients with deficient mismatch repair (dMMR) or high microsatellite instability (MSI-H), its effectiveness in proficient mismatch repair (pMMR) or microsatellite stable (MSS) CRC remains limited. Recent advances highlight the gut microbiota as a potential modulator of anti-tumor immunity.
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