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Randomised Badger Culling Trial lacks evidence for proactive badger culling effect on tuberculosis in cattle: comment on Mills et al. 2024, Parts I & II.
bioRxiv
September 2024
Herpetofauna Consultants International, Suffolk, UK.
Article Synopsis
- The rebuttal by Mills et al. (2024) defends the statistical methods used in the Randomised Badger Culling Trial (RBCT), particularly the choice of count over rate for assessing bovine tuberculosis herd incidence.
- * The authors argue that previous analyses overfit data and incorrectly apply Bayesian methods, prioritizing model fit over practical predictive power in a small dataset context.
- * Ultimately, the RBCT's findings on the impact of badger culling on bovine tuberculosis incidence are deemed unconvincing, with modern veterinary insights suggesting the original conclusions still stand but require a nuanced understanding.
Penetration of isavuconazole into the epithelial lining fluid of patients with pulmonary fungal infections. Comment on: 'Pharmacokinetics of isavuconazole at different target sites in healthy volunteers after single and multiple intravenous infusions'.
J Antimicrob Chemother
September 2024
Paris Centre University Cochin Hospital, Infectious Diseases Stewardship Team, AP-HP, Paris, France.
Response to Letter to the Editor From van Os et al: "Persistently Decreased Quality of Life and its Determinants in Previous Illicit Androgen Users".
J Clin Endocrinol Metab
December 2024
Department of Nephrology and Endocrinology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, DK-2100, Denmark.
Optical Genome Mapping in Prenatal Diagnosis: Democratizing Comprehensive Cytogenomic Testing.
Clin Chem
June 2024
The Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, United States.
An International Expert-Based CONsensus on Indications and Techniques for aoRtic balloOn occLusion in the Management of Ruptured Abdominal Aortic Aneurysms (CONTROL-RAAA).
J Endovasc Ther
December 2023
Division of Vascular Surgery, Department of Experimental and Clinical Sciences, University of Brescia, Brescia, Italy.
Objective: To report on the recommendations of an expert-based consensus on the indications, timing, and techniques of aortic balloon occlusion (ABO) in the management of ruptured abdominal aortic aneurysms (rAAA).
Methods: Eleven facilitators created appropriate statements regarding the study issues that were voted on using a 4-point Likert scale with open-comment fields, by a selected panel of international experts (vascular surgeons and interventional radiologists) using a 3-round modified Delphi consensus procedure (study period: January-April 2023). Based on the experts' responses, only the statements reaching grade A (full agreement ≥75%) or B (overall agreement ≥80% and full disagreement <5%) were included in the final study report.
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