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Hypokalemic paralysis secondary to tenofovir induced fanconi syndrome. | LitMetric

Hypokalemic paralysis secondary to tenofovir induced fanconi syndrome.

Indian J Sex Transm Dis AIDS

Department of Medicine and Infectious Diseases, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.

Published: December 2015

Tenofovir induced fanconi syndrome (FS) presenting as hypokalemic paralysis is an extremely rare complication in patients on anti-retroviral therapy. We report a 50-year-old male with acquired immunodeficiency syndrome on tenofovir-based anti-retroviral therapy who presented with acute onset quadriparesis. On evaluation, he was found to have hypokalemia with hypophosphatemia, glucosuria and proteinuria suggesting FS. He regained normal power in limbs over next 12 h following correction of hypokalemia. Ours would be the second reported case in India.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660566PMC
http://dx.doi.org/10.4103/0253-7184.167176DOI Listing

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