Antimicrobial drug treatment of travelers' diarrhea is known to increase the risk for colonization with extended-spectrum β-lactamase-producing Enterobacteriaceae. Among 288 travelers with travelers' diarrhea, the colonization rate without medications was 21%. For treatment with loperamide only, the rate was 20%; with antimicrobial drugs alone, 40%; and with loperamide and antimicrobial drugs, 71%.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696706PMC
http://dx.doi.org/10.3201/eid2201.151272DOI Listing

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