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Metalated arylmethylisonitriles readily add to 2-chloropyridines to afford imidazo[1,5-a]pyridines. Analogous additions to imidoyl chlorides and a chloroquinoline provide imidazoles and an imidazo[1,5-a]quinolone which, like imidazo[1,5-a]pyridines, are valuable heterocycles for pharmaceutical synthesis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729585 | PMC |
| http://dx.doi.org/10.1039/c5cc08724d | DOI Listing |
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