Biological trace element research

1559-072017222016AugBiological trace element researchBiol Trace Elem ResHigh Iodine and Salt Intakes and Obesity do not Modify the Thyroid Function in Mexican Schoolchildren.290298290-29810.1007/s12011-015-0591-1Mexico is considered as a nutritional transition country with a high prevalence of overweight and obesity, and recent studies have reported a high iodine intake in children. Both high iodine intake and obesity have been associated with thyroid dysfunction. Our aim was to assess iodine and salt intake and thyroid function in Mexican schoolchildren with normal weight and obesity. A cross-sectional study was performed during 2012-2013 in schoolchildren from Queretaro, Mexico. Six hundred seventy-eight schoolchildren were evaluated to obtain nutrition status, urinary iodine concentration (UIC) and thyroid volume (TVol). The prevalence of overweight and obesity was 47.3 %, the median UIC was 428 μg/L and TVol was normal in all schoolchildren; however, obese girls had a higher TVol than normal weight at the age of 8, 10 and 12 years. A subsample of schoolchildren was divided in 6-8 and 9-12-year-old groups, in order to compare thyroid function (thyrotropin, free T4, and anti-thyroid antibodies); iodine and salt intake were estimated with 24-h urinary samples. No differences in thyroid function were observed in both age groups. In the 6-8-year-old group, obese schoolchildren had higher iodine intake than normal-weight children (415.5 vs. 269.1 μg/day, p < 0.05), but no differences in salt intake. In contrast, in the 9-12-year-old group, obese schoolchildren had higher salt intake than normal-weight children (6.2 vs. 3.8 g/day, p < 0.05), but no differences in iodine intake. Dietary patterns could explain the differences between both age groups. Further studies are needed to identify the main sources of iodine intake in Mexican populations.Méndez-VillaLorenaLLaboratorio de Endocrinología y Nutrición, Departamento de Investigación Biomédica, Facultad de Medicina, Universidad Autónoma de Querétaro, Clavel 200. Fracc. Prados de la Capilla, Querétaro, Querétaro, CP. 76176, Mexico.García-SolísPabloPLaboratorio de Endocrinología y Nutrición, Departamento de Investigación Biomédica, Facultad de Medicina, Universidad Autónoma de Querétaro, Clavel 200. Fracc. Prados de la Capilla, Querétaro, Querétaro, CP. 76176, Mexico. pablo.garcia@uaq.mx.Solís-SJuan CarlosJCLaboratorio de Endocrinología y Nutrición, Departamento de Investigación Biomédica, Facultad de Medicina, Universidad Autónoma de Querétaro, Clavel 200. Fracc. Prados de la Capilla, Querétaro, Querétaro, CP. 76176, Mexico.García-GutiérrezDavid GustavoDGLaboratorio de Endocrinología y Nutrición, Departamento de Investigación Biomédica, Facultad de Medicina, Universidad Autónoma de Querétaro, Clavel 200. Fracc. Prados de la Capilla, Querétaro, Querétaro, CP. 76176, Mexico.Pérez-MoraValeria AlejandraVALaboratorio de Endocrinología y Nutrición, Departamento de Investigación Biomédica, Facultad de Medicina, Universidad Autónoma de Querétaro, Clavel 200. Fracc. Prados de la Capilla, Querétaro, Querétaro, CP. 76176, Mexico.Robles-OsorioLudivinaLFacultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Querétaro, Mexico.Sampson-ZaldívarEduardoEDepartamento de Radiología, Vida Care Diagnóstico, Querétaro, Mexico.engJournal Article20151222