The diagnosis of infectious disease is best achieved, and appropriate therapy best effectuated, by isolation and identification of the causative agent. With appropriate exercise of foresight, the necessary procedures can be carried out readily on tissue samples obtained at surgery for morphologic study. Close cooperation among involved specialists permits microbiologic investigation of surgical specimens to be carried out routinely with results highly beneficial to patient care. Four cases illustrating the value of such studies in facilitating diagnosis and treatment are described.
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