UVEAL MELANOMA EXTENSION TO THE OPTIC CHIASM.

Retin Cases Brief Rep

Departments of *Ophthalmology, and†Anatomic Pathology, Mayo Clinic, Rochester, Minnesota; and‡Gainesville Eye Physicians, Gainesville, Florida.

Published: September 2016

Purpose: Case report describing a patient who developed intracranial extension of a uveal melanoma through the optic nerve.

Methods: We reviewed the patient's medical history and images. A 41-year-old woman who was blind in one eye had a uveal melanoma that extended through the optic nerve into the optic chiasm and involved the hypophysis. The patient then developed metastasis.

Results: The patient developed uveal melanoma extension into the optic chiasm through the optic nerve resulting in a visual field defect in the fellow eye.

Conclusion: Uveal melanoma extension through the optic nerve is a devastating complication, which occurs anywhere from 0.6% to 3.7% in patients with uveal melanoma. If enucleation of the affected eye is performed, a representative portion of the optic nerve should be excised to decrease the risk of extension. Patients with phthisical eyes should undergo appropriate imaging techniques to prevent a missed diagnosis of optic nerve involvement.

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Source
http://dx.doi.org/10.1097/ICB.0000000000000163DOI Listing

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