Objective: In the present investigation, ethanolic extract of Cyperus rotundus (EECR) rhizomes was evaluated for antidiabetic activity in streptozotocin (STZ)-induced diabetic swiss mice.
Materials And Methods: After administration of EECR extract for 3 weeks, the body weight, blood glucose, biomarker enzymes (serum glutamic pyruvic transaminase [SGPT] and serum glutamic oxaloacetic transaminase [SGOT]), and plasma lipid levels were measured in STZ-induced diabetic mice.
Results: The ethanolic extract at dose levels of 250 and 500 mg/kg body weight revealed significant antidiabetic activity, improvement in body weight, and reduction in elevated biochemical parameters such as SGPT, SGOT, cholesterol, and triglyceride levels.
Conclusion: These experimental findings seemed to indicate the use of this plant in traditional Indian medicine for the treatment of diabetes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678986 | PMC |
| http://dx.doi.org/10.4103/0975-7406.168028 | DOI Listing |
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