In tumoral cells, gene regulation mechanisms are severely altered. Genes that do not react normally to their regulators' activity can provide explanations for the tumoral behavior, and be characteristic of cancer subtypes. We thus propose a statistical methodology to identify the misregulated genes given a reference network and gene expression data.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674863 | PMC |
| http://dx.doi.org/10.1186/1752-0509-9-S6-S6 | DOI Listing |
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