ViralEpi v1.0: a high-throughput spectrum of viral epigenomic methylation profiles from diverse diseases.

Epigenomics

Bioinformatics Centre, Institute of Microbial Technology, Council of Scientific & Industrial Research (CSIR), Sector 39-A, Chandigarh-160036, India.

Published: January 2016

Aims: To develop a computational resource for viral epigenomic methylation profiles from diverse diseases.

Materials & Methods: Methylation patterns of Epstein-Barr virus and hepatitis B virus genomic regions are provided as web platform developed using open source Linux-Apache-MySQL-PHP (LAMP) bundle: programming and scripting languages, that is, HTML, JavaScript and PERL.

Results: A comprehensive and integrated web resource ViralEpi v1.0 is developed providing well-organized compendium of methylation events and statistical analysis associated with several diseases. Additionally, it also facilitates 'Viral EpiGenome Browser' for user-affable browsing experience using JavaScript-based JBrowse.

Conclusion: This web resource would be helpful for research community engaged in studying epigenetic biomarkers for appropriate prognosis and diagnosis of diseases and its various stages.

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Source
http://dx.doi.org/10.2217/epi.15.95DOI Listing

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