AI Article Synopsis

Article Abstract

cgpPindel is a modified version of Pindel that is optimized for detecting somatic insertions and deletions (indels) in cancer genomes and other samples compared to a reference control. Post-hoc filters remove false positive calls, resulting in a high-quality dataset for downstream analysis. This unit provides concise instructions for both a simple 'one-shot' execution of cgpPindel and a more detailed approach suitable for large-scale compute farms.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097606PMC
http://dx.doi.org/10.1002/0471250953.bi1507s52DOI Listing

Publication Analysis

Top Keywords

cgppindel identifying
4
identifying somatically
4
somatically acquired
4
acquired insertion
4
insertion deletion
4
deletion events
4
events paired
4
paired sequencing
4
sequencing cgppindel
4
cgppindel modified
4

Similar Publications

cgpPindel is a modified version of Pindel that is optimized for detecting somatic insertions and deletions (indels) in cancer genomes and other samples compared to a reference control. Post-hoc filters remove false positive calls, resulting in a high-quality dataset for downstream analysis. This unit provides concise instructions for both a simple 'one-shot' execution of cgpPindel and a more detailed approach suitable for large-scale compute farms.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!