cgpPindel is a modified version of Pindel that is optimized for detecting somatic insertions and deletions (indels) in cancer genomes and other samples compared to a reference control. Post-hoc filters remove false positive calls, resulting in a high-quality dataset for downstream analysis. This unit provides concise instructions for both a simple 'one-shot' execution of cgpPindel and a more detailed approach suitable for large-scale compute farms.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097606 | PMC |
http://dx.doi.org/10.1002/0471250953.bi1507s52 | DOI Listing |
Curr Protoc Bioinformatics
December 2015
Cancer Genome Project, Wellcome Trust Sanger Institute, Cambridge, United Kingdom.
cgpPindel is a modified version of Pindel that is optimized for detecting somatic insertions and deletions (indels) in cancer genomes and other samples compared to a reference control. Post-hoc filters remove false positive calls, resulting in a high-quality dataset for downstream analysis. This unit provides concise instructions for both a simple 'one-shot' execution of cgpPindel and a more detailed approach suitable for large-scale compute farms.
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