A major goal of the treatment of cleft lip and palate is to improve the esthetic acceptability of the face. It is assumed that an improved esthetic appearance is associated with significant psychosocial benefits, but there is almost no empiric support for this assumption. Researchers have been hindered in the study of this problem because scales to measure severity of facial impairment of clefts have not been available; however, standard scales of facial impairment have been developed for occlusal traits, orthognathic structure, and facial attractiveness. The purpose of this paper is to describe selected theoretic and methodologic approaches to scaling the esthetic acceptability of various facial characteristics and to discuss how these methods have been applied to the study of relationships between facial morphology and psychosocial variables. It is argued that these approaches may be useful, as models for the development of scales of severity of cleft impairment, to clinicians and researchers who are interested in the treatment of facial clefts.
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J Med Internet Res
January 2025
Department of Radiation Oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Background: Primary intracranial germ cell tumors (iGCTs) are highly malignant brain tumors that predominantly occur in children and adolescents, with an incidence rate ranking third among primary brain tumors in East Asia (8%-15%). Due to their insidious onset and impact on critical functional areas of the brain, these tumors often result in irreversible abnormalities in growth and development, as well as cognitive and motor impairments in affected children. Therefore, early diagnosis through advanced screening techniques is vital for improving patient outcomes and quality of life.
View Article and Find Full Text PDFNeuropsychol Rehabil
January 2025
School of Psychological Sciences, Macquarie University, Marsfield, NSW 2109, Australia.
Prosopagnosia is a neurological disorder; characterized by an impairment in facial recognition. It can occur from acquired prosopagnosia (occurring in approximately 5.6% of the population), or from developmental prosopagnosia (occurring in approximately 2% of the population).
View Article and Find Full Text PDFJMIR Med Inform
January 2025
Fundación INTRAS, Valladolid, Spain.
Background: This review explores the potential of virtual reality (VR) and artificial intelligence (AI) to identify preclinical cognitive markers of Alzheimer disease (AD). By synthesizing recent studies, it aims to advance early diagnostic methods to detect AD before significant symptoms occur.
Objective: Research emphasizes the significance of early detection in AD during the preclinical phase, which does not involve cognitive impairment but nevertheless requires reliable biomarkers.
J Clin Nurs
January 2025
Ankara Hospital, Directory of Nursing Services, Baskent University, Ankara, Turkey.
Aim: To examine the factors affecting the ability of ostomates to perform activities of daily living and manage ostomy self-care.
Design: Mix method design.
Method: This study was undertaken through survey (descriptive and clinical characteristics form and Katz Activities of Daily Living (ADL)) for collecting the quantitative data (n = 60) and semi-structured interviews were conducted with patients unable to perform ostomy self-care for collecting qualitative data (n = 12) between January 2023 and December 2023.
Rev Neurol (Paris)
January 2025
Unité neurovasculaire, Centre Hospitalier Métropole Savoie, Chambéry, France. Electronic address:
Introduction: Prehospital identification of stroke patients with large vessel occlusion (LVO) is crucial to optimize transport to an endovascular thrombectomy (EVT)-capable center. Existing scores require medical or paramedical expertise and specific teachings. We aimed to validate a simple prehospital phone-based score for LVO identification.
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