Objective: To assess hormonal changes in nonthyroidal illness syndrome (NTIS) in full-term newborns (NT) with sepsis.
Materials And Methods: We included 28 NT with sepsis divided into 2 groups according to the time of normalization of serum and clinical indicators of infection: group A(A), 16 NT with improvement in up to 8 days; and group B(B), 12 NT improvement after 8 days. Among the 28 NT, 15 NT progressed to septic shock, with 5 NT group A and 10 NT in group B. NT were excluded when they showed severe sepsis and asphyxia, and congenital malformations, as well as those whose mothers had thyroid disease and IUGR.
Results: 17 NT (60.7%) presented NTIS. Low T3 was observed in NTIS in 10 NT (58.8%), and low T4 and T3 in 5 NT (29.5%), all of them with septic shock. Two NT showed mixed changes (11.7%). After sepsis was cured, there was no hormonal change, except in 3 NT. Administration of dopamine, furosemide, and corticosteroids did not affect the results.
Conclusions: This study indicates that nonthyroidal illness syndrome may be transiently present during sepsis in full-term newborns, especially in cases of prolonged sepsis. Low T3 can occur without changes in reverse T3 (different from adults), and low T4 and T3 occur mainly in patients with septic shock.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1590/2359-3997000000111 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Age-related impact of phenobarbital in suppressing prenatal alcohol exposure-related seizures in developing rats.
Alcohol
December 2024
Howard University College of Medicine, Department of Physiology and Biophysics, Washington, DC 20059, United States. Electronic address:
Prenatal alcohol exposure (PAE) during pregnancy can increase the prevalence of N-methyl-D-aspartate (NMDA)-induced generalized tonic-clonic seizures (GTCSs) in developing rats. However, it is unclear whether phenobarbital (PB) can suppress these PAE-related seizures. To explore this knowledge gap, we investigated the effects of acute PB treatment on NMDA-induced seizures in postpartum rats, prenatally exposed to alcohol on gestational day 18 (GD18), at two developmental stages: day 7 (P7), the equivalent of pre-term neonates, and day 15 (P15), the equivalent of full-term neonates.
View Article and Find Full Text PDF[Topical issues of early diagnosis of hearing loss in newborn children].
Vestn Otorinolaringol
December 2024
Mendeleev Russian University of Chemical Technology, Moscow, Russia.
A group of Russian specialists dealing with the problems of auditory function in premature babies touches upon important issues of early detection of hearing loss and deafness in this contingent of children born before the date of physiological birth. The purpose of the article was to argue the need for a personalized approach to the diagnosis of auditory function in premature and full-term babies depending on the timing of gestation and their somatic state at the time of birth, as well as the comprehensive rehabilitation of children with hearing loss and deafness. The article describes the advantages of the previously developed computer program Multiplicity of audiological monitoring in children of the first year of life with risk factors for hearing loss and deafness.
View Article and Find Full Text PDFMotor predictors of cortical brain development and full-IQ in children born extremely preterm with and without discrete white matter abnormalities.
Brain Struct Funct
December 2024
Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Aim: To describe the cortical brain development and full-IQ performance in middle school age children after extremely preterm (EPT) birth considering discrete white matter abnormalities (WMA). In addition, to assess possible early motor predictors of cortical brain development and full-IQ in children born EPT with and without discrete WMA diagnosed at 10 years.
Methods: T1-weighted MRI images from fifty-one children born before 27 weeks' gestation and 40 full-term born controls (M=10.
Maternal and neonatal short-term outcome after vaginal breech delivery >36 weeks of gestation with and without MRI-based pelvimetric measurements: a Hannover retrospective cohort study.
J Perinat Med
December 2024
Department of Obstetrics, Gynecology and Reproductive Medicine, Hannover Medical School, Hannover, Germany.
Objectives: Planning the mode of delivery of a full-term breech singleton remains a challenging task. The aim of this work is to compare the neonatal and maternal short-term outcomes after planned vaginal delivery and caesarean section and to evaluate the influence of an MRI pelvimetry on the short-term outcomes in order to provide appropriate advice to pregnant women with breech presentation.
Methods: This is a retrospective monocentric analysis of all deliveries with singleton pregnancies from breech presentation >36 + 0 weeks of gestation between 08/2021 and 09/2023.
Music medicine and music therapy in neonatal care: a scoping review of passive music listening research applications and findings on infant development and medical practice.
BMC Pediatr
December 2024
Independent Researcher, Pune, India.
Background: In recent years, the use of music as a therapeutic and developmental tool for infants, especially within neonatal intensive care units (NICUs), has seen a surge in interest. Despite a growing body of research underscoring the potential benefits of music therapy and music medicine in enhancing infant development and aiding medical practices, the specific characteristics of music that maximize these benefits remain poorly understood.
Objectives: This scoping review aims to provide a comprehensive foundation by mapping the existing literature on passive music listening and identifying gaps, trends, and patterns that are crucial precursors to the development of best practices.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!