Common femoral artery puncture for ilio-femoral angioplasty can be hazardous or cumbersome in specific situations that require upper limb access (presence of a hostile groin, previous femoral surgery, cross-over maneuver in the setting of bifurcated aortic graft or pre-existing iliac kissing stents). The brachial artery is an alternative access site that is burdened with significant local complication rates. As in the coronary setting, feasibility and safety of transradial peripheral angioplasty has been reported in the recent literature. Procedural success rates ranged from 87% to 100%. No major access site bleeding was observed. Procedure and fluoroscopy time were not substantially increased, and decreased along with the learning curve. The majority of reports were limited to iliac lesions treatment, due to the lack of long-shaft and dedicated devices. Our experience showed the feasibility of this technique in iliac lesions but also in superficial femoral and popliteal artery procedures. Radial access can be used in situations where femoral approach is unsuitable and as first-line approach in the setting of ambulatory procedures. Although devices evolve, main limitations remain related to the lack of longer introducer sheaths and the absence of specific rescue devices and drug-eluting balloons. As a conclusion, radial access for endovascular ilio-femoral procedures is currently a promising alternative to femoral and humeral access in selected patients with the possibility of same-day discharge, and could progressively be considered when planning peripheral procedures.
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Anal Chem
January 2025
Department of Cancer Biology and Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California 91010, United States.
Extracellular vesicles (EVs), membrane-encapsulated nanoparticles shed from all cells, are tightly involved in critical cellular functions. Moreover, EVs have recently emerged as exciting therapeutic modalities, delivery vectors, and biomarker sources. However, EVs are difficult to characterize, because they are typically small and heterogeneous in size, origin, and molecular content.
View Article and Find Full Text PDFJ Clin Med
December 2024
Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
: Cangrelor provides rapid platelet inhibition, making it a potential option for out-of-hospital cardiac arrest (OHCA) survivors undergoing percutaneous coronary intervention (PCI). However, clinical data on its use after OHCA are limited. This study investigates in-hospital outcomes of cangrelor use in this population.
View Article and Find Full Text PDFCureus
December 2024
Department of Ophthalmology, UT Southwestern Medical Center, Dallas, USA.
An 83-year-old male with a history of radial keratotomy and laser-assisted in situ keratomileusis (LASIK) presented with symptoms of a non-resolving corneal ulcer in the right eye that had been present for five months. The patient was treated with antibacterial, antiviral, and antifungal medications over that period, with multiple recurrences that prompted referral to our tertiary center for management. Following a 48-hour cessation of all medications, a corneal biopsy was performed which grew .
View Article and Find Full Text PDFActa Cardiol
January 2025
Department of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA.
Background: Trans-radial coronary angiogram (TR-CAG) has gained popularity due to lower complication rates compared to transfemoral access. Operators can use either conventional catheters, such as Judkins, or single dedicated catheters, such as Tiger-II. This meta-analysis compared the safety and efficacy of Tiger-II versus Judkins catheters in TR-CAG.
View Article and Find Full Text PDFJ Neurointerv Surg
January 2025
Radiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Background: We aim to share our experience of transradial access (TRA) for cerebral angiography and intervention in five patients ranging from 6 days to 7 months of age.
Methods: In this institutional review board-approved, retrospective case series, we reviewed all patients who underwent TRA for cerebral angiography with and without intervention. We describe three techniques for radial artery cannulation, namely: (1) bareback; (2) with a micropuncture sheath; and (3) with an intravenous catheter.
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