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http://dx.doi.org/10.2450/2015.0091-15DOI Listing

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Atrial fibrillation (AF) remains the most common cardiac arrhythmia worldwide and is associated with significant morbidity and mortality. The European Society of Cardiology (ESC)/European Association for Cardio-Thoracic Surgery (EACTS) have recently released the 2024 guidelines for the management of AF. This review highlights 10 novel aspects of the ESC/EACTS 2024 Guidelines.

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  • Cardiovascular electronic devices can identify atrial high-rate episodes (AHREs), but the specific predictors of significant AHREs were not well understood until this study.
  • In a study of 145 patients, around 30.3% experienced AHREs over a six-month period, with data collected on risk factors using Cox regression analysis.
  • Key risk factors linked to the development of AHREs included prior use of anti-arrhythmic drugs, history of paroxysmal supraventricular tachycardia, percentage of premature atrial contractions recorded on ECG, and left ventricular global longitudinal strain measurements.
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  • A recent study found that cognitive behavioral therapy for symptom preoccupation related to paroxysmal atrial fibrillation (AF-CBT) improved quality of life but its effects on physiological factors like heart rate variability (HRV), physical activity, and sleep were unclear.
  • In the study, 127 patients were divided into two groups, one receiving AF-CBT and the other AF education for 10 weeks, with assessments conducted before, after treatment, and at three months.
  • Results showed that while AF-CBT significantly reduced insomnia severity, it did not affect heart rate variability, physical activity levels, or overall sleep duration, suggesting the therapy's benefits may be more psychological than physiological.
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  • Epilepsy is a neurological disorder that affects quality of life and involves changes in brain activity, neurotransmitter imbalances, and GABA receptor dysfunction, with its causes still not fully understood.
  • Thyroid hormones are important for brain function and can influence seizure activity by regulating oxidative stress and neurotransmitter levels, so defects in their signaling may lead to more frequent seizures and neurodevelopmental disorders.
  • Traditional antiseizure medications may disrupt thyroid hormone levels, with some, like phenobarbital and carbamazepine, potentially causing hypothyroidism, while newer medications like levetiracetam don’t impact thyroid levels, highlighting the complex interplay between seizures and thyroid hormone dynamics.
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  • A study was conducted on individuals aged 70 and older to assess the frequency and burden of atrial fibrillation (AF) using a 14-day electrocardiograph monitor.
  • Out of 5,684 participants, 4.4% were found to have AF, with the majority having paroxysmal AF of low burden; the median time spent in AF was only about 75 minutes.
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