Cognitive rehabilitation for mild cognitive impairment (MCI) and early Alzheimer's disease is readily available to the geriatric population. Initial evidence suggests that techniques incorporating motivational strategies to enhance treatment engagement may provide more benefit than computerised training alone. Seventy four adults with subclinical cognitive decline were randomly assigned to computerised cognitive training (CCT), Cognitive Vitality Training (CVT), or an Active Control Group (ACG), and underwent neuropsychological evaluations at baseline and four-month follow-up. Significant differences were found in changes in performance on the Modified Mini Mental State Examination (mMMSE) and measures of verbal learning and memory across treatment groups. Experimental groups showed greater preservation of functioning on the mMMSE than the ACG group, the CVT group performed better than the ACG group on one measure of verbal learning and both measures of verbal memory, and the CCT group performed better than the ACG group on one measure of verbal learning and one measure of verbal memory. There were no significant group differences between the CVT and CCT groups on measures of verbal learning or memory. It was concluded that computerised cognitive training may offer the most benefit when incorporated into a therapeutic milieu rather than administered alone, although both appear superior to more generic forms of cognitive stimulation.
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http://dx.doi.org/10.1080/09602011.2015.1118389 | DOI Listing |
BMC Psychiatry
December 2024
Department of Clinical, Neuro- and Developmental Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Background: There is robust evidence that posttraumatic stress disorder (PTSD) is associated with neurocognitive deficits, such as executive dysfunction or memory dysfunction. Eye Movement Desensitization and Reprocessing (EMDR) is an evidence-based treatment for PTSD, in which eye movements (EMs) are performed during traumatic memory retrieval. We examined whether Eye Movement Desensitization (EMD) improves neurocognitive functioning in PTSD patients, in comparison with a retrieval-only control condition without EMs.
View Article and Find Full Text PDFJ Exp Child Psychol
December 2024
Department of Behavioral Sciences and Learning, Linköping University, Campus Valla, SE-581 83 Linköping, Sweden.
The purpose of this study was to pinpoint which mixture of cognitive abilities and number abilities underlies young children's early mental arithmetic learning (i.e., skill development) and to examine to what extent this mixture is akin to the mixture underlying children's early arithmetic performance.
View Article and Find Full Text PDFJ Biomed Phys Eng
December 2024
Department of Medical Physics & Biomedical Eng., School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Background: Acquiring new knowledge necessitates alterations at the synaptic level within the brain. Glutamate, a pivotal neurotransmitter, plays a critical role in these processes, particularly in learning and memory formation. Although previous research has explored glutamate's involvement in cognitive functions, a comprehensive understanding of its real-time dynamics remains elusive during memory tasks.
View Article and Find Full Text PDFJ Neurol Sci
December 2024
Computational and Translational Neuroscience Laboratory, Institute of Cognitive Sciences and Technologies, National Research Council (CTNLab-ISTC-CNR), Via Gian Domenico Romagnosi 18A, Rome 00196, Italy; AI2Life s.r.l., Innovative Start-Up, ISTC-CNR Spin-Off, Via Sebino 32, Rome 00199, Italy. Electronic address:
Alzheimer's disease (AD), the most common neurodegenerative disorder world-wide, presents sex-specific differences in its manifestation and progression, necessitating personalized diagnostic approaches. Current procedures are often costly and invasive, lacking consideration of sex-based differences. This study introduces an explainable machine learning (ML) system to predict and differentiate the progression of AD based on sex, using non-invasive, easily collectible predictors such as neuropsychological test scores and sociodemographic data, enabling its application in every day clinical settings.
View Article and Find Full Text PDFClin Neuropsychol
December 2024
Kennedy Krieger Institute, Baltimore, MD, USA.
To determine the clinical utility of teleneuropsychology (teleNP) services in screening for cognitive concerns in a population of children and adolescents presenting with long COVID. This cross-sectional study evaluated 76 pediatric patients (64% female, = 13.48, = 2.
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