Objective: To examine associations of individual exposure and knowledge of resuscitation mechanics and prognosis with specific decision: Do Not Resuscitate (DNR), Full Code (FC) or Undecided (UD).
Methods: Cross-sectional questionnaire at 3 sites: geriatric assessment center, internal medicine resident clinic, and inpatient palliative care service.
Results: 407 completed the questionnaire: 27% identified as DNR, 24% as FC and 49% as UD. Few (11.8%) respondents reported discussion of DNR status with their primary care doctor. DNR choice was associated with knowledge of DNR mechanics, OR=2.30 (95%CI: 1.23-4.30), physician discussion, OR=5.58 (95%CI: 2.39-13.04) and confidence in understanding own health problems, OR=2.89 (95%CI: 1.04-8.04). FC choice was associated with knowledge of FC mechanics, OR=2.01 (95%CI: 1.03-3.93) and media code exposure, OR=3.80 (95%CI: 1.46-9.92). Knowledge of resuscitation prognosis was negatively associated with FC, OR =0.48 (95%CI: 0.23-0.98).
Conclusion: Many individuals lack knowledge or understanding of resuscitation procedure, its risks, and prognosis. Educational efforts, for both patients and healthcare professionals, are needed to improve individual knowledge needed for informed decision.
Practice Implications: Scheduled time for physician-patient discussion remains important for education about individual health conditions and risk/benefits related to resuscitation.
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http://dx.doi.org/10.1016/j.pec.2015.11.027 | DOI Listing |
Alzheimers Dement
December 2024
University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA.
Background: Reversible post-translational modifications, phosphorylation and dephosphorylation, on tau protein play a critical role in the microtubule (MT) modulation. However, abnormal tau phosphorylation, which occurs in tauopathies such as Alzheimer's disease (AD), causes the dissociation of tau from MTs. The dissociated tau then aggregates into sequent forms from soluble oligomers to paired helical filaments (PHF), and insoluble neurofibrillary tangles (NFTs), a hallmark of AD.
View Article and Find Full Text PDFNeuropsychiatr Dis Treat
December 2024
Growth, Development and Mental Health Center of Children and Adolescents, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Chongqing, 400014, People's Republic of China.
Purpose: There is no consensus on whether cognitive measures among attention deficit hyperactivity disorder (ADHD) subtypes exhibit more similarities or differences, and most of them have been conducted on English-speaking subjects, lacking cross-cultural perspectives. The present study was aimed at investigating the intelligence structures of school-age children with ADHD who speak Chinese, using a multicenter and large sample size approach, offering some references for clinicians.
Patients And Methods: 772 children aged 6 to 12 years with ADHD took part in the cross-sectional study.
Sci Rep
January 2025
Department of Surgery, Trinity St. James's Cancer Institute, Trinity Translational Medicine Institute, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.
Integration of multi-omic data for the purposes of biomarker discovery can provide novel and robust panels across multiple biological compartments. Appropriate analytical methods are key to ensuring accurate and meaningful outputs in the multi-omic setting. Here, we extensively profile the proteome and transcriptome of patient pancreatic cyst fluid (PCF) (n = 32) and serum (n = 68), before integrating matched omic and biofluid data, to identify biomarkers of pancreatic cancer risk.
View Article and Find Full Text PDFInt J Legal Med
January 2025
University Department of Forensic Sciences, University of Split, R. Boškovića 33, Split, 21000, Croatia.
This study aimed to test age-related changes in sternal fusion and sternal-rib cartilage ossification on multi-slice computed tomography (MSCT) images of the Croatian population. The additional aim was to develop models to estimate age and provide an interface for the model's application and validation. This retrospective study was conducted on 144 MSCT images of the sternal region, and the developed models were tested on 36 MSCT images.
View Article and Find Full Text PDFSemin Oncol Nurs
December 2024
Faculty of Health Sciences, Department of Nursing, Antalya Bilim University, Antalya, Türkiye.
Objective: Pediatric oncology nursing is a challenging and emotionally exhausting profession. Understanding the challenges and struggles faced by pediatric oncology nurses can help to create targeted interventions that will improve their well-being and enhance the quality of care for children with cancer and their families. This study aimed to explore the challenges and struggles nurses face in their daily care practices.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!