AI Article Synopsis
- PEth is a specific biomarker for long-term alcohol consumption, accumulating in the body after repeated drinking, making it useful for monitoring drinking behavior.
- In a study of 142 blood samples with varying blood alcohol concentrations (BAC), PEth levels were analyzed, revealing that specific thresholds could distinguish between moderate and excessive drinking.
- The findings showed that high concentrations of PEth (≥ 700 ng/mL for 16:0/18:1 and ≥ 300 ng/mL for 16:0/18:2) could indicate prolonged excessive drinking, even when BAC is below the legal driving limit of 1.6‰, suggesting the need for additional assessments of driving ability.
Article Abstract
Phosphatidylethanol (PEth) is considered as specific biomarker of alcohol consumption. Due to accumulation after repeated drinking, PEth is suitable to monitor long-term drinking behavior. To examine the applicability of PEth in "driving under the influence of alcohol" cases, 142 blood samples with blood alcohol concentrations (BAC) ranging from 0.0-3.12‰ were analyzed for the presence of PEth homologues 16:0/18:1 (889 ± 878 ng/mL; range
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http://dx.doi.org/10.1007/s00414-015-1300-5 DOI Listing Publication Analysis
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