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Background: Mapping biopsy (MB) can evaluate superficial ductal spread (SDS) through the histopathological diagnosis of cholangiocarcinoma, enabling the selection of an appropriate surgical procedure. This retrospective study evaluated the efficacy of MB using a novel sheath system in distal cholangiocarcinoma (dCCA) cases.

Methods: A total of 199 cholangiocarcinoma cases underwent preoperative diagnosis.

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A high recurrence rate is undesirable after treatment of common bile duct (CBD) stones. A major risk factor identified for recurrence is that invasive techniques, including surgical or endoscopic treatments, will impair the biliary tract system either by direct incision of the CBD or by cutting or dilating the ampulla of Vater. During endoscopic treatment, two main assisted methods for lithotomy, sphincterotomy and papillary balloon dilation, can result in different degrees of damage to the structure and function of the sphincter of Oddi (SO), contributing to slowing of biliary excretion, cholestasis, biliary bacterial infection, and promotion of bile duct stone recurrence.

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Article Synopsis
  • Patients with achalasia are at risk for cancer due to chronic inflammation, and the study explores using two procedures—endoscopic submucosal dissection (ESD) and peroral endoscopic myotomy (POEM)—in one operation to minimize trauma and improve recovery.
  • A 65-year-old man with type II achalasia and suspected esophageal lesions underwent this combined approach, which involved creating a tunnel for myotomy and then removing the suspicious lesion via ESD.
  • The results showed successful removal of the lesion with high-grade dysplasia, reduced symptoms, and no recurrence, indicating that tailored endoscopic techniques can provide effective and less invasive treatment for achalasia patients with early-stage cancer.
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The Endoscopic Management of Zenker's Diverticulum: A Comprehensive Review.

Diagnostics (Basel)

September 2024

Gastroenterology and Gastrointestinal Endoscopy Division, IRCCS San Raffaele Institute, Via Olgettina 60, 20132 Milan, Italy.

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  • Zenker's Diverticulum (ZD) is a common throat condition caused by a herniation of tissue, leading to difficulty swallowing (dysphagia) in most patients.
  • Traditional surgery for ZD has high technical challenges and can result in significant complications, prompting interest in less invasive endoscopic methods.
  • Newer endoscopic techniques like Zenker-POEM and Per Oral Endoscopic Septomyotomy offer alternative treatment options, which are discussed along with their pros, cons, and potential future developments.
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