Intravascular large B-cell lymphoma involving gastrointestinal stromal tumor: a case report and literature review.

Diagn Pathol

Department of Pathology, Guangdong General Hospital, Guangdong, Academy of Medical Science, Guangzhou, 510080, China.

Published: December 2015

Background: Intravascular large B-cell lymphoma is a rare and aggressive lymphoma with a dismal prognosis. Synchronous intravascular large B-cell lymphoma involving gastrointestinal stromal tumor has not previously been documented.

Case Presentation: We report a case of a 61-year-old Chinese woman who presented with high fever of unknown origin for 20 days, and hematemesis, melena for 2 days. A computed tomography scan revealed a mass lesion located in the anterior wall of the stomach. Surgery was performed to remove the tumor and histopathology showed a gastrointestinal stromal tumor and a synchronous intravascular large B-cell lymphoma. The patient refused further treatment and died 4 months after surgery.

Conclusions: To the best of our knowledge, this case represents the first report of synchronous intravascular large B-cell lymphoma involving a gastrointestinal stromal tumor.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681078PMC
http://dx.doi.org/10.1186/s13000-015-0446-2DOI Listing

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