Catalytic reductive N-alkylation of amines using carboxylic acids.

Chem Commun (Camb)

School of Chemistry, University Park, University of Nottingham, Nottingham, NG7 2RD, UK.

Published: January 2016

We report a catalytic reductive alkylation reaction of primary or secondary amines with carboxylic acids. The two-phase process involves silane mediated direct amidation followed by catalytic reduction.

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Source
http://dx.doi.org/10.1039/c5cc08881jDOI Listing

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