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| http://dx.doi.org/10.4103/0971-4065.161517 | DOI Listing |
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Importance of early use of tolvaptan in hyponatremic acutely decompensated heart failure patients, a retrospective study.
Egypt Heart J
January 2025
Department of Cardiology, Division of Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
Background: Hyponatremia is one of the complicating findings in acute decompensated heart failure. Decrease in cardiac output and systemic blood pressure triggers activation of renin-angiotensin-aldosterone system, antidiuretic hormone, and norepinephrine due to the perceived hypovolemia. Fluid-overloaded heart failure patients are commonly treated with loop diuretics, acutely decompensated heart failure patients tend to be less responsive to conventional oral doses of a loop diuretic, while other different diuretics could work in different part of nephron circulation system.
View Article and Find Full Text PDFCoronavirus Disease 2019 (COVID-19)-Induced Hyponatremia: A Challenging Geriatric Case.
Cureus
October 2024
Family Medicine, Beckley Appalachian Regional Healthcare (ARH) Hospital, Beckley, USA.
Article Synopsis
- * Initial thoughts about her condition pointed to improper regulation of water in the body, but further investigation indicated that her symptoms might be due to poor fluid intake and a misdiagnosed kidney issue.
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Excess dietary sodium restores electrolyte and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron.
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From the Department of Biological Sciences, St. Jude Children's Research Hospital, Memphis, TN 30105.
The maintenance of fluid and electrolyte homeostasis by the kidney requires proper folding and trafficking of ion channels and transporters in kidney epithelia. Each of these processes requires a specific subset of a diverse class of proteins termed molecular chaperones. One such chaperone is GRP170, which is an Hsp70-like, endoplasmic reticulum (ER)-localized chaperone that plays roles in protein quality control and protein folding in the ER.
View Article and Find Full Text PDFCutaneous Herpes Zoster Infection as a Rare Etiology of Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH): A Case Report.
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Takotsubo syndrome induced by severe hyponatraemia in mineralocorticoid-responsive hyponatraemia of the elderly: a case report.
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October 2024
Division of Cardiology, Department of Internal Medicine, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-ku, Yokohama, Kanagawa 227-8501, Japan.
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