We present a focal-beamforming-enhanced formulation of the distorted Born iterative method (DBIM) for microwave breast imaging. Incorporating beamforming into the imaging algorithm has the potential to mitigate the effect of noise on the image reconstruction. We apply the focal-beamforming-enhanced DBIM algorithm to simulated array measurements from two MRI-derived, anatomically realistic numerical breast phantoms and compare its performance to that of the DBIM formulated with two non-focal schemes. The first scheme simply averages scattered field data from reciprocal antenna pairs while the second scheme discards reciprocal pairs. Images of the dielectric properties are reconstructed for signal-to-noise ratios (SNR) ranging from 35 dB down to 0 dB. We show that, for low SNR, the focal beamforming algorithm creates reconstructions that are of higher fidelity with respect to the exact dielectric profiles of the phantoms as compared to reconstructions created using the non-focal schemes. At high SNR, the focal and non-focal reconstructions are of comparable quality.
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http://dx.doi.org/10.1109/TAP.2014.2344096 | DOI Listing |
Int J Nanomedicine
January 2025
Key Laboratory of Medical Cell Biology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People's Republic of China.
Introduction: The anti-cancer properties of zinc oxide-doped carbon dots (CDs/ZnO) in inhibiting triple-negative breast cancer (TNBC) progression merit more investigation.
Methods: With citric acid as the carbon source, urea applied as the nitrogen source, and zinc oxide (ZnO) used as a reactive dopant, CDs/ZnO were synthesized by microwave heating in the current study, followed by the characterization and biocompatibility assessments. Subsequently, the anti-cancer capabilities of CDs/ZnO against TNBC progression were evaluated by various biochemical and molecular techniques, including viability, proliferation, migration, invasion, adhesion, clonogenicity, cell cycle distribution, apoptosis, redox homeostasis, metabolome, and transcriptome assays of MDA-MB-231 cells.
Int J Biol Macromol
December 2024
Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology (IUST), Tehran, Iran. Electronic address:
Chitosan, a versatile biopolymer derived from chitin, is increasingly recognized in the milk industry for its multifunctional applications in drug delivery, smart packaging, and biosensor development. This review provides a comprehensive analysis of recent advances in chitosan production techniques. These include chemical, biological, and novel methods such as deep eutectic solvents (DES), microwave-assisted approaches, and laser-assisted processes.
View Article and Find Full Text PDFJ Control Release
December 2024
Laboratory of Integrative Medicine, Clinical Research Center for Breast, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China. Electronic address:
Bioorg Chem
December 2024
Laboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Health Sciences, Central University of Punjab, Bathinda 151 401, India. Electronic address:
In this study, we herein report the design, synthesis, and anticancer assessment of a series of new 4-substituted 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines. The synthesis involved key intermediates such as the 2-aminoester derivative, which underwent a series of reactions to produce compounds 7a-7t. The optimized SAr reactions, utilizing microwave irradiation in DMF, led to high yields and efficient preparation of the desired compounds.
View Article and Find Full Text PDFCompr Rev Food Sci Food Saf
January 2025
Parul Institute of Technology, Parul University, Vadodara, Gujarat, India.
The margarine market is growing globally due to its lower cost, ease of availability, large-scale commercialization, and expanding market in the bakery and confectionary industries. Butter contains greater amounts of saturated fat and has been associated with cardiovascular diseases. The trans fats generated through the hydrogenation process have several adverse impacts on human health, such as the risk of atherosclerosis, coronary heart disease, postmenopausal breast cancer, vision and neurological system impairment, type II diabetes, and obesity.
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