Novel Functions of Renin Precursors in Homeostasis and Disease.

Physiology (Bethesda)

University of Virginia School of Medicine, Child Health Research Center, Charlottesville, Virginia

Published: January 2016

Renin progenitors appear early and are found in multiple tissues throughout the embryo. Besides their well known role in blood pressure and fluid homeostasis, renin progenitors participate in tissue morphogenesis, repair, and regeneration, and may integrate immune and endocrine responses. In the bone marrow, renin cells offer clues to understand normal and neoplastic hematopoiesis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698453PMC
http://dx.doi.org/10.1152/physiol.00039.2015DOI Listing

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