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Implementation of a Consensus Set of Hypervariable Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeat Loci in Mycobacterium tuberculosis Molecular Epidemiology. | LitMetric
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Implementation of a Consensus Set of Hypervariable Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeat Loci in Mycobacterium tuberculosis Molecular Epidemiology.

Alberto Trovato Silva Tafaj Simone Battaglia Riccardo Alagna Donika Bardhi Perlat Kapisyzi Silvana Bala Migena Haldeda Emanuele Borroni Hasan Hafizi Daniela Maria Cirillo

J Clin Microbiol

Division of Infectious Disease, Immunology and Transplantation, IRCCS San Raffaele Scientific Institute, Milan, Italy

Published: February 2016

This study shows that the addition of a consensus 4-locus set of hypervariable mycobacterial interspersed repetitive-unit-variable-number tandem repeat (MIRU-VNTR) loci to the spoligotyping-24-locus MIRU-VNTR typing strategy is a well-standardized approach that can contribute to an improvement of the true cluster definition while retaining high typeability in non-Beijing strains.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733199PMC
http://dx.doi.org/10.1128/JCM.02945-15DOI Listing

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