Purpose: Recently, a fatigue threshold obtained during submaximal repetitive isometric knee extensor contractions was related to V˙O2max measured during cycling and to exercise endurance. However, test duration is quite long (20-30 min in young people) to be of practical and possibly clinical use. The purpose of the present study was to test the day-to-day reliability of a newly developed short test that assessed the fatigue threshold during a submaximal test with the knee extensors.
Methods: Fifteen healthy young males were tested three times, once using the original long protocol (5-min blocks of repetitive unilateral isometric knee extensor contractions with stepwise (5% MVC) increases of force) and twice using a new shorter protocol. In the latter, force increased by 2% MVC every 30 s, starting at 15% MVC (all contractions were 3 s on, 2 s off). The fatigue threshold was defined as the force where the EMG/force ratio started to increase and, compared with the force, at which deoxygenated hemoglobin concentration ([HHb]) increased steeply (HHb threshold).
Results: The EMG/force threshold during the short trials was reached after 3.9 ± 1.5 min of submaximal exercise and similar (P > 0.05) between days. The EMG/force threshold showed good reliability (intraclass correlation coefficient = 0.87, SEM = 2.2%) and did not differ between (P > 0.05) the short (31.1% ± 7.6% MVC) and long tests (30.5% ± 6.2% MVC), with a significant relation (r = 0.71) between both tests. Similar results (P > 0.05) were found for the HHb threshold.
Conclusion: In young healthy men, a fatigue threshold can be detected during repetitive isometric knee extensor contractions using a short submaximal test, which may be suitable for untrained or frail people and patients.
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http://dx.doi.org/10.1249/MSS.0000000000000832 | DOI Listing |
PLoS Negl Trop Dis
January 2025
Department of Public Health, Faculty of Health Sciences, Mbale Campus, Busitema University, Mbale City, Uganda.
Introduction: Visceral leishmaniasis (VL) also known as Kala-azar is one of the neglected tropical diseases (NTD) of public health importance. Despite being a disease of a long history, the condition remains poorly studied especially in East Africa. For instance, whereas, the geographical location of the disease is known, there is a stark paucity of data on the burden, risk factors and clinical outcomes of this contribution in Northeastern Uganda.
View Article and Find Full Text PDFEur J Case Rep Intern Med
December 2024
Internal Medicine, Holy Family Hospital, Rawalpindi, Pakistan.
Background: Andersen-Tawil syndrome (ATS) is a rare autosomal dominant disorder caused by variants in the gene. It is associated with periodic paralysis, dysmorphic features and cardiac arrhythmias. The syndrome exhibits incomplete penetrance, leading to a broad spectrum of clinical manifestations, making diagnosis challenging.
View Article and Find Full Text PDFJ Rehabil Assist Technol Eng
January 2025
Department of Health Sciences, Faculty of Medicine, Health and Human Sciences, Macquarie University, NSW, Sydney, Australia.
Spinal cord injury and stroke are neurological disorders that lead to aerobic deconditioning and increased likelihood of cardiovascular disease. Sessions of at least 20 minutes of moderate-to-vigorous intensity exercise is recommended but decreased mobility limits engagement in such exercise. The aim of the study was to assess whether individuals can achieve exercise recommendations with the assistance of an end-effector robot assisted gait trainer (E-RAGT).
View Article and Find Full Text PDFCancer Med
January 2025
Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Objective: Cancer-related fatigue is one of the most common burdens of cancer patients. To date, most studies focused on fatigue during or after treatment. However, investigation of pretreatment fatigue is crucial to identify causal or risk factors other than cancer therapy and to enable timely fatigue management.
View Article and Find Full Text PDFFront Neurol
December 2024
Department of Clinical Neurosciences, Division of Physical Medicine and Rehabilitation, University of Calgary, Calgary, AB, Canada.
Background: Although guidelines support aerobic exercise in sub-acute mild traumatic brain injury (mTBI), evidence for adults with persisting post-concussive symptoms (PPCS) after mTBI is lacking. The objective was to evaluate the impact of a sub-symptom threshold aerobic exercise intervention on overall symptom burden and quality of life in adults with PPCS.
Methods: This prospective cohort study was nested within the ACTBI Trial (Aerobic Exercise for treatment of Chronic symptoms following mild Traumatic Brain Injury).
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