Fatal case of acute gastroenteritis with multiple viral coinfections.

J Clin Virol

Laboratory of Virology, University Hospital of Grenoble, Grenoble, France; CNRS, Unit for Virus Host-Cell Interactions, 38042 Grenoble, France; Université Grenoble Alpes, Unit for Virus Host-Cell Interactions, 38042 Grenoble, France.

Published: January 2016

We report a fatal case of acute gastroenteritis in a child with autism spectrum disorder. Multiple viral coinfections were detected by PCR in the patient's stool and digestive biopsy specimens. As viral detection is not necessarily associated with symptomatic disease, a semi-quantitative approach using cycle treshold values was proposed for the clinical interpretation of PCR. We discuss whether concomitant viral infections could be a risk factor for severe outcome in gastroenteritis cases. Individual risk factors are also addressed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129220PMC
http://dx.doi.org/10.1016/j.jcv.2015.11.026DOI Listing

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