AI Article Synopsis
- Zebrafish are a valuable model for studying vertebrate development due to their genetic manipulability and relevance to disease research.
- Genome editing techniques have become popular for precisely modifying the zebrafish genome, increasing their utility in scientific studies.
- The review outlines practical genome editing methods and strategies for detecting specific genetic alterations in zebrafish research.
Article Abstract
Zebrafish is a powerful model for the study of vertebrate development, being amenable to a wide range of genetic and other manipulations to probe the molecular basis of development and its perturbation in disease. Over recent years, genome editing approaches have become increasingly used as an efficient and sophisticated approach to precisely engineer the zebrafish genome, which has further enhanced the utility of this organism. This review provides a practical overview of genome editing and its application in zebrafish research, including alternate strategies for introducing and screening for specific genetic changes.
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| http://dx.doi.org/10.1093/bfgp/elv051 | DOI Listing |
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