Euphorpekone A (1) and euphorpekone B (2), two new diterpenoids, 3β-hydroxy-25-methyloxylanosta-8,23-diene, a new triterpenoid (3), together with a known triterpenoid, 3β,25-dihydroxylanosta-8,23-diene (4), were isolated from Euphorbia pekinensis Rupr. Their structures were elucidated on the basis of UV, IR, 1D ((1)H, (13)C, NOE) and 2D ((1)H-(1)H COSY, HSQC, HMBC) NMR, HR-ESI-MS, X-ray diffraction analysis, and CD method.
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http://dx.doi.org/10.1080/10286020.2015.1118466 | DOI Listing |
Zhongguo Zhong Yao Za Zhi
November 2024
Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine Nanjing 210023, China.
This study aimed to investigate the toxicity differences of the ethyl acetate fraction of Euphorbiae Pekinensis Radix before and after vinegar processing and explore the detoxification mechanism of vinegar processing using non-targeted metabolomics. The changes in terpenoid components in the ethyl acetate fraction before and after vinegar processing were analyzed using UFLC-Q-TOF-MS. Normal rats were orally administered the raw and vinegar-processed ethyl acetate fractions of Euphorbia Pekinensis Radix.
View Article and Find Full Text PDFGene
February 2025
Department of Life Sciences, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, Republic of Korea. Electronic address:
Euphorbia fauriei, a perennial plant endemic to South Korea, exhibits both morphological characteristics and intricate genetic identities akin to E. pekinensis. This study aimed to provide clarity on the taxonomic status of E.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
October 2024
University Institute of Pharma Sciences, Chandigarh University, Mohali, Punjab, India.
Neurodegenerative disorders are characterized by neuronal degradation, dysfunction, or death within the CNS. Oxidative and inflammatory stress play crucial roles in the pathogenesis of various neurodegenerative diseases. The interplay between these stressors and dysregulated cellular signaling pathways contributes to neurodegeneration.
View Article and Find Full Text PDFPhytomedicine
December 2024
Wuxi Cancer Institute, Wuxi Institute of Integrated Chinese and Western Medicine, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu 214062, China; Laboratory of Cancer Epigenetics, Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu 214122, China. Electronic address:
Nat Prod Res
August 2024
Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, Kunming, PR China.
Rupr. is a traditional herb generally distributed in most areas of China, north Korea and Japan. The dried roots of Rupr.
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