AI Article Synopsis

  • The study investigates how common acute pancreatitis is among patients with acute brucellosis and what factors contribute to its occurrence.
  • It involved analyzing data from adult brucellosis patients, checking their blood samples for various indicators, including specific antibody levels and enzyme concentrations.
  • Results showed that patients with both conditions had higher levels of certain enzymes and blood sugar, but lower hemoglobin, which might help in evaluating the severity of their conditions.

Article Abstract

Objectives: To determine the prevalence and determinants of acute pancreatitis in patients with acute brucellosis.

Methods: Adult patients with brucellosis were retrospectively recruited. Brucellosis and acute pancreatitis were diagnosed according to standard criteria. Laboratory analyses included Wright agglutination titre, serum biochemical parameters and blood count.

Results: Patients with acute pancreatitis (n = 21) had significantly higher Wright agglutination titres, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, γ-glutamyl transpeptidase, amylase, lipase and serum glucose concentrations, and significantly lower haemoglobin concentrations and haematocrit than patients with brucellosis alone (n = 326).

Conclusions: Hyperglycaemia, anaemia, and liver transaminase and cholestatic enzyme concentrations may represent new approaches for assessing disease severity in patients with brucellosis and acute pancreatitis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536568PMC
http://dx.doi.org/10.1177/0300060515583078DOI Listing

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