Interferon-gamma (IFNγ) neutralizing autoantibodies are associated with disseminated nontuberculous mycobacterial infections. We report a previously healthy Thai woman with disseminated tuberculosis and high-titer IFNγ-neutralizing autoantibodies, who developed a severe inflammatory reaction during anti-tuberculosis treatment. IFNγ contributes to host control of tuberculosis but appears inessential for tuberculosis paradoxical reactions.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772847 | PMC |
| http://dx.doi.org/10.1093/cid/civ995 | DOI Listing |
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