Determining thresholds using adaptive procedures and psychometric fits: evaluating efficiency using theory, simulations, and human experiments.

Exp Brain Res

Jenks Vestibular Physiology Lab, Massachusetts Eye and Ear Infirmary, 243 Charles St., Boston, MA, 02114, USA.

Published: March 2016

When measuring thresholds, careful selection of stimulus amplitude can increase efficiency by increasing the precision of psychometric fit parameters (e.g., decreasing the fit parameter error bars). To find efficient adaptive algorithms for psychometric threshold ("sigma") estimation, we combined analytic approaches, Monte Carlo simulations, and human experiments for a one-interval, binary forced-choice, direction-recognition task. To our knowledge, this is the first time analytic results have been combined and compared with either simulation or human results. Human performance was consistent with theory and not significantly different from simulation predictions. Our analytic approach provides a bound on efficiency, which we compared against the efficiency of standard staircase algorithms, a modified staircase algorithm with asymmetric step sizes, and a maximum likelihood estimation (MLE) procedure. Simulation results suggest that optimal efficiency at determining threshold is provided by the MLE procedure targeting a fraction correct level of 0.92, an asymmetric 4-down, 1-up staircase targeting between 0.86 and 0.92 or a standard 6-down, 1-up staircase. Psychometric test efficiency, computed by comparing simulation and analytic results, was between 41 and 58% for 50 trials for these three algorithms, reaching up to 84% for 200 trials. These approaches were 13-21% more efficient than the commonly used 3-down, 1-up symmetric staircase. We also applied recent advances to reduce accuracy errors using a bias-reduced fitting approach. Taken together, the results lend confidence that the assumptions underlying each approach are reasonable and that human threshold forced-choice decision making is modeled well by detection theory models and mimics simulations based on detection theory models.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831214PMC
http://dx.doi.org/10.1007/s00221-015-4501-8DOI Listing

Publication Analysis

Top Keywords

simulations human
8
human experiments
8
mle procedure
8
1-up staircase
8
detection theory
8
theory models
8
efficiency
6
human
5
staircase
5
determining thresholds
4

Similar Publications

Dust emissions from open-pit mining pose a significant threat to environmental safety and human health. Currently, the range of dust suppressants used in coal mining is limited, often failing to account for their suitability across various stockpiles. This oversight results in poor infiltration after application, leading to insufficient crust formation and reduced durability.

View Article and Find Full Text PDF

Blood components play a crucial role in maintaining human health and accurately detecting them is essential for medical diagnostics. A cutting-edge sensor utilizing PCF revealed to precisely identify a wide range of blood components with WBCs (white blood cells), RBCs (red blood cells), HB (hemoglobin), platelets, and plasma. A numerical analysis was performed using COMSOL Multiphysics software to assess the capabilities of the sensor.

View Article and Find Full Text PDF

Voltage-gated sodium channels (VGSCs) in the peripheral nervous system shape action potentials (APs) and thereby support the detection of sensory stimuli. Most of the nine mammalian VGSC subtypes are expressed in nociceptors, but predominantly, three are linked to several human pain syndromes: while Nav1.7 is suggested to be a (sub-)threshold channel, Nav1.

View Article and Find Full Text PDF

Background Detection and segmentation of lung tumors on CT scans are critical for monitoring cancer progression, evaluating treatment responses, and planning radiation therapy; however, manual delineation is labor-intensive and subject to physician variability. Purpose To develop and evaluate an ensemble deep learning model for automating identification and segmentation of lung tumors on CT scans. Materials and Methods A retrospective study was conducted between July 2019 and November 2024 using a large dataset of CT simulation scans and clinical lung tumor segmentations from radiotherapy plans.

View Article and Find Full Text PDF

[Which alternatives could be considered for health students learning about falls in older patients? Focus groups].

Geriatr Psychol Neuropsychiatr Vieil

December 2024

Faculté de santé, Université d'Angers, France, Département de médecine aiguë gériatrique, Centre de recherche sur l'autonomie et la longévité, hôpital universitaire d'Angers, France.

Older patients are at risk of falling, making fall prevention a critical component of training for future health professionals. To understand the expectations of health students regarding falls in the elderly, four consecutive focus groups were organized at the Angers hospital. The aim was to assess students' views on the effectiveness of using an educational or serious game to complement their traditional training.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!