Carcinoma ex pleomorphic adenoma originating from ectopic salivary gland in the neck region: case report.

Gland Surg

1 Department of Otorhinolaryngology, 2 Department of Pathology, Faculty of Medicine, University of Mersin, Mersin, Turkey.

Published: December 2015

AI Article Synopsis

  • Carcinoma ex pleomorphic adenoma (CEPA) is a type of malignant tumor that develops from either new or recurring pleomorphic adenomas, primarily found in the parotid gland but can also appear in other salivary glands and occasionally in the head and neck region.
  • A case study of a 72-year-old woman revealed a 7.5 cm neck mass originating from an atypical area related to submandibular gland tissue.
  • The report highlights diagnostic challenges and discusses approaches to treatment, referencing current research in the field.

Article Abstract

Carcinoma ex pleomorphic adenoma (CEPA) is the malignant salivary gland tumor originating from primary (de novo) or recurrent pleomorphic adenoma. Although parotid gland is the most common site, it can also be seen in submandibular gland or minor salivary glands. It can be seen rarely in head and neck region, such as oral cavity, trachea, nasal cavity and lacrimal gland. Although pleomorphic adenoma cases originating from ectopic salivary gland tissue in the neck region are present in the English literature, there is no published pleomorphic adenoma ex carcinoma case. In this case report we presented a CEPA as a 7.5 cm long neck mass in a 72-year-old woman originating from the submandibular region apart from submandibular gland. Difficulties in diagnosis and way to appropriate treatment are discussed with current literature.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647010PMC
http://dx.doi.org/10.3978/j.issn.2227-684X.2015.01.03DOI Listing

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