AI Article Synopsis
- β2-agonists help improve airflow by relaxing the airway smooth muscle, thus increasing the airway diameter.
- There are two main types: short-acting β2-agonists (SABAs), like albuterol and terbutaline, which work quickly for 2 to 6 hours, and long-acting β2-agonists (LABAs), such as salmeterol and formoterol, which last longer and require use twice a day.
- SABAs are typically used for quick relief during asthma attacks or before exercise, while LABAs are beneficial for controlling symptoms over a longer period, especially at night.
Article Abstract
β2-agonists reduce airflow limitation by improving airway diameter as a consequence of a direct action on airway smooth muscle. β;2-agonists can be broadly classified according to their duration of action: short-acting β2-agonists (SABAs), including albuterol, terbutaline and fenoterol, have pharmacodynamics halflives between 2 and 6 h and long-acting β2-agonists (LABAs), including salmeterol and formoterol, require twice daily treatment. SABAs are often used as needed for asthma exacerbations and before exercise in the presence of exercise-induced bronchospasm. LABAs provide longer symptom control, which is a particularly useful feature for preventing night-time symptoms. There are two main LABAs, salmeterol and formoterol. This review focused on the recent data published on this topic.
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