AI Article Synopsis
- Understanding the redox chemistry in cells is crucial for their health, as it plays a significant role in cell functions and disease associations.
- Developing chemical tools to measure redox biology is important for distinguishing between healthy oxidative states and those linked to chronic diseases.
- This review summarizes advancements in redox probes and highlights future research directions needed in this emerging field.
Article Abstract
The redox chemistry of the cell is key to its function and health, and the development of chemical tools to study redox biology is important. While fluxes in oxidative state are essential for healthy cell function, a chronically elevated oxidative capacity is linked to disease. It is therefore essential that probes of biological redox states distinguish between these two conditions by the reversible sensing of changes over time. In this review, we discuss the current progress towards such probes, and identify key directions for future research in this nascent field of vital biological interest.
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| http://dx.doi.org/10.1002/anie.201506353 | DOI Listing |
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