NHPI and palladium cocatalyzed aerobic oxidative acylation of arenes through a radical process.

Chem Commun (Camb)

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. 38, Beijing 100191, China. and State Key Laboratory of Organometallic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.

Published: January 2016

The NHPI and palladium cocatalyzed radical oxidative acylation of arenes with aldehydes and alcohols as acyl equivalents via selective C-H functionalization has been described. Molecular oxygen, the most environmentally friendly oxidant, was used as the terminal oxidant in this catalytic cycle.

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Source
http://dx.doi.org/10.1039/c5cc08945jDOI Listing

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